Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 13/20 | 0.67 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.61 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.61 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.61 |
| ▸ | LDHA | P00338 | 1/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | FBP1 | P09467 | 1/20 | 0.61 |
| ▸ | SRC | P12931 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.61 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.61 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.61 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.61 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677945 | 0.94 | RNASEL (0.76) | RNASELDNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL10778019 | 0.94 | RNASEL (0.66) | RNASELTRPM2SRCP2RY2P2RY1 | |
| SCHEMBL28263983 | 0.92 | P2RY1 (0.63) | RNASELDNPH1PRKAB2TRPM2LDHA | |
| Cystetine Triphosphate SCHEMBL10778035 | 0.90 | P2RY1 (0.65) | RNASELTRPM2SRCP2RY2P2RY1 | |
| SCHEMBL1940955 | 0.89 | RNASEL (0.76) | RNASELDNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL4970108 | 0.89 | RNASEL (0.84) | RNASELDNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL29452474 | 0.88 | P2RX3 (0.65) | RNASELDNPH1PRKAB2TRPM2LDHA | |
| Adenosine Phosphate SCHEMBL28920925 | 0.88 | P2RY1 (0.80) | RNASELDNPH1PRKAB2TRPM2LDHA | |
| Adenosine Phosphate SCHEMBL29390023 | 0.88 | P2RY1 (0.80) | RNASELDNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL29350567 | 0.88 | P2RY2 (0.65) | RNASELP2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3705493-A1 | EGFR-HOMING DOUBLE-STRANDED RNA VECTOR FOR SYSTEMIC CANCER TREATMENT | TargImmune Therapeutics AG (CH) | 2020-09-09 | — | — | EP | disclosed |
| EP-3098239-B1 | EGFR-HOMING DOUBLE-STRANDED RNA VECTOR FOR SYSTEMIC CANCER TREATMENT | TARGIMMUNE THERAPEUTICS AG (CH) | 2019-10-23 | — | — | EP | disclosed |
| EP-3098239-A1 | EGFR-HOMING DOUBLE-STRANDED RNA VECTOR FOR SYSTEMIC CANCER TREATMENT | Levitzki, Alexander (IL) | 2016-11-30 | — | — | EP | disclosed |
| EP-2379597-B1 | EGFR-HOMING DOUBLE-STRANDED RNA VECTOR FOR SYSTEMIC CANCER TREATMENT | LEVITZKI ALEXANDER (IL) | 2016-08-10 | — | — | EP | disclosed |
| US-9006406-B2 | EGFR-homing double-stranded RNA vector for systemic cancer treatment | Levitzki, Alexander (IL) | 2015-04-14 | — | — | US | disclosed |
| US-20120021006-A1 | EGFR-HOMING DOUBLE-STRANDED RNA VECTOR FOR SYSTEMIC CANCER TREATMENT | TARGIMMUNE THERAPEUTICS AG (CH) | 2012-01-26 | — | — | US | disclosed |