Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HMGCR | P04035 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4321817 | 0.98 | KDM4E (0.47) | ALDH1A1KDM4ESMN1; SMN2NPC1HTT | |
| Trifluoroacetic Acid SCHEMBL4326117 | 0.95 | TP53 (0.49) | ALDH1A1KDM4ESMN1; SMN2NPC1HTT | |
| SCHEMBL13578097 | 0.94 | ALDH1A1 (0.55) | ALDH1A1KDM4ESMN1; SMN2NPC1HTT | |
| SCHEMBL13578102 | 0.93 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2NPC1HTT | |
| Trifluoroacetic Acid SCHEMBL4327711 | 0.91 | KMT2A (0.47) | ALDH1A1KDM4ESMN1; SMN2NPC1HTT | |
| SCHEMBL13578100 | 0.89 | TP53 (0.51) | ALDH1A1KDM4ESMN1; SMN2NPC1HTT | |
| Trifluoroacetic Acid SCHEMBL4341463 | 0.89 | SMN1; SMN2 (0.40) | ALDH1A1KDM4ESMN1; SMN2NPC1HTT | |
| Trifluoroacetic Acid SCHEMBL4327011 | 0.89 | TP53 (0.44) | ALDH1A1CNR2MAPTLMNAHPGD | |
| Trifluoroacetic Acid SCHEMBL4320038 | 0.89 | CASP3 (0.49) | PTGER4CNR2KMT2A | |
| Trifluoroacetic Acid SCHEMBL4326406 | 0.87 | TP53 (0.51) | ALDH1A1KDM4ESMN1; SMN2HTTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | CNR2, CNR1, TRPV1 | ALDH1A1 2838/4885KDM4E 2430/4885SMN1; SMN2 3374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.