Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 2/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 1/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.76 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.48 |
| ▸ | GABRP | O00591 | 2/20 | 0.48 |
| ▸ | GABRD | O14764 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.48 |
| ▸ | GABRE | P78334 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lormetazepam SCHEMBL29565149 | 1.00 | OPRK1 (1.00) | OPRK1PDE4DCHRM2ADRA2ALMNA | |
| Lormetazepam SCHEMBL29484438 | 1.00 | OPRK1 (1.00) | OPRK1PDE4DCHRM2ADRA2ALMNA | |
| (S)-Lormetazepam SCHEMBL43268 | 1.00 | OPRK1 (1.00) | OPRK1PDE4DCHRM2ADRA2ALMNA | |
| Lormetazepam SCHEMBL1758605 | 0.94 | OPRK1 (0.89) | OPRK1PDE4DCHRM2ADRA2ALMNA | |
| Lormetazepam SCHEMBL21295409 | 0.92 | OPRK1 (0.85) | OPRK1PDE4DCHRM2ADRA2ALMNA | |
| Flutemazepam SCHEMBL1006405 | 0.88 | OPRK1 (0.79) | OPRK1PDE4DCHRM2ADRA2ALMNA | |
| Flutemazepam SCHEMBL1006406 | 0.88 | OPRK1 (0.79) | OPRK1PDE4DCHRM2ADRA2ALMNA | |
| Temazepam SCHEMBL5503177 | 0.86 | OPRK1 (1.00) | OPRK1PDE4DCHRM2ADRA2ALMNA | |
| Temazepam SCHEMBL29463 | 0.86 | OPRK1 (1.00) | OPRK1PDE4DCHRM2ADRA2ALMNA | |
| SCHEMBL6944910 | 0.86 | OPRK1 (0.76) | OPRK1PDE4DCHRM2ADRA2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6755 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260115161-A1 | 2-HYDROXY-OCTADECENE-9-CIS-OATE FOR USE IN THE TREATMENT OF ONCOLOGICAL PATHOLOGIES AND NEUROPATHIC PAIN | LAMINAR PHARMACEUTICALS S A (ES) | 2026-04-30 | — | — | US | claimed |
| EP-4719552-A1 | INDUCTION OF GENERAL ANESTHESIA IN ADULTS UNDERGOING ELECTIVE SURGERY | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2026-04-08 | — | — | EP | claimed |
| US-20260076953-A1 | METHODS OF DIAGNOSING AND TREATING ADHD IN BIOMARKER POSITIVE SUBJECTS | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2026-03-19 | — | — | US | claimed |
| EP-3507371-B1 | COMPOSITIONS FOR TREATING DISEASES AND DISORDERS OF THE NERVOUS SYSTEM | UNIV RUTGERS (US) | 2026-01-28 | — | — | EP | claimed |
| EP-4663187-A1 | 2-HYDROXY-OCTADECENE-9-CIS-OATE FOR USE IN THE TREATMENT OF ONCOLOGICAL PATHOLOGIES AND NEUROPATHIC PAIN | Laminar Pharmaceuticals, S.A. (ES) | 2025-12-17 | — | — | EP | claimed |
| US-20250375421-A1 | METHODS OF USING DMT | SHULMAN WILLIAM (US) | 2025-12-11 | — | — | US | claimed |
| US-12396981-B2 | Methods of using DMT | SHULMAN WILLIAM (US) | 2025-08-26 | — | — | US | claimed |
| US-20250120962-A1 | NONSELECTIVE METABOTROPIC GLUTAMATE RECEPTOR ACTIVATORS FOR TREATMENT OF ATTENTION DEFICIT DISORDER AND 22Q SYNDROME | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2025-04-17 | — | — | US | claimed |
| EP-4023222-B1 | NONSELECTIVE METABOTROPIC GLUTAMATE RECEPTOR ACTIVATOR FOR TREATMENT OF 22Q SYNDROME | CHILDRENS HOSPITAL PHILADELPHIA (US) | 2024-12-18 | — | — | EP | claimed |
| WO-2024251110-A1 | INDUCTION OF GENERAL ANESTHESIA IN ADULTS UNDERGOING ELECTIVE SURGERY | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-12-12 | — | — | WO | claimed |
| EP-0682943-A1 | Oil-in-water emulsion containing lorazepam or lormetazepam | GESELLSCHAFT FÜR MEDIZINISCHE FORSCHUNG UND WEITERBILDUNG e.V. GMF (DE) | 1995-11-22 | — | — | EP | claimed |
| EP-0584285-A1 | IMPROVEMENTS IN BENZODIAZEPINE TREATMENT BY CHOLINESTERASE INHIBITORS | Snorrason, Ernir (IS) | 1994-03-02 | — | — | EP | claimed |
| US-5288497-A | Compositions of oral dissolvable medicaments | THE UNIVERSITY OF UTAH (US) | 1994-02-22 | — | — | US | claimed |
| US-5288498-A | Compositions of oral nondissolvable matrixes for transmucosal administration of medicaments | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1994-02-22 | — | — | US | claimed |
| EP-0579435-A1 | Cyclodextrin complexation | CYCLOPS h.f. (IS) | 1994-01-19 | — | — | EP | claimed |
| US-5248678-A | Administering adenosine receptor antagonist and a GABA antagonist | FRACTAL LABORATORIES, INC. (US) | 1993-09-28 | — | — | US | claimed |
| WO-1992020328-A2 | IMPROVEMENTS IN BENZODIAZEPINE TREATMENT BY CHOLINESTERASE INHIBITORS | SNORRASON ERNIR (IS) | 1992-11-26 | — | — | WO | claimed |
| EP-0515301-A2 | Improvements in benzodiazepine treatment by cholinesterterase inhibitors | Snorrason, Ernir (IS) | 1992-11-25 | — | — | EP | claimed |
| US-4721709-A | Novel pharmaceutical compositions containing hydrophobic practically water-insoluble drugs adsorbed on pharmaceutical excipients as carrier; process for their preparation and the use of said compositions | PYARE SETH (CH) | 1988-01-26 | — | — | US | claimed |
| US-4065451-A | CNS DEPRESSANTS | AMERICAN HOME PRODUCTS (US) | 1977-12-27 | — | — | US | claimed |