Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mandelic Acid SCHEMBL8757198 | 0.98 | LMNA (0.62) | LMNAMAPK1CYP2D6CYP1A2HPGD | |
| SCHEMBL7563030 | 0.89 | LMNA (0.50) | LMNAMAPK1CYP2D6CYP1A2HPGD | |
| Atrolactamide SCHEMBL31758013 | 0.85 | LMNA (0.58) | LMNAMAPK1CYP2D6CYP1A2HPGD | |
| Methane SCHEMBL17958770 | 0.84 | CYP1A2 (0.50) | MAPK1CYP2D6CYP1A2MAPTKMT2A | |
| SCHEMBL197251 | 0.82 | MAPT (0.52) | MAPK1CYP2D6CYP1A2MAPTKMT2A | |
| SCHEMBL21557850 | 0.82 | MAPT (0.52) | MAPK1CYP2D6CYP1A2MAPTKMT2A | |
| SCHEMBL153694 | 0.82 | MAPT (0.52) | MAPK1CYP2D6CYP1A2MAPTKMT2A | |
| SCHEMBL4326795 | 0.82 | MAPT (0.52) | MAPK1CYP2D6CYP1A2MAPTKMT2A | |
| SCHEMBL198241 | 0.82 | MAPT (0.52) | MAPK1CYP2D6CYP1A2MAPTKMT2A | |
| Benzylic Acid SCHEMBL7559896 | 0.81 | LMNA (0.67) | LMNAMAPK1CYP2D6CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511844-B1 | X-ray microscope | XRPRO SCIENCES INC (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2084519-B1 | X-RAY FLUORESCENCE ANALYSIS METHOD | LOS ALAMOS NAT SECURITY LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-2084519-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | Los Alamos National Security, LLC (US) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008127291-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2008-10-23 | — | — | WO | disclosed |