Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | SNCA | P37840 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4335398 | 0.88 | NPC1 (0.75) | MTNR1AMTNR1BPTGS1PTGS2TRPV1 | |
| SCHEMBL9935308 | 0.86 | SNCA (0.74) | MTNR1AMTNR1BPTGS1PTGS2TRPV1 | |
| SCHEMBL4325288 | 0.86 | MTNR1A (0.61) | MTNR1AMTNR1BPTGS1PTGS2TRPV1 | |
| SCHEMBL4330537 | 0.85 | MTNR1A (0.60) | MTNR1AMTNR1BPTGS1PTGS2TRPV1 | |
| SCHEMBL5341652 | 0.85 | MEN1 (0.73) | MTNR1AMTNR1BTRPV1MEN1KMT2A | |
| SCHEMBL15145341 | 0.81 | PTGS1 (0.76) | PTGS1PTGS2TRPV1MEN1KMT2A | |
| SCHEMBL15145365 | 0.81 | PTGS1 (0.79) | PTGS1PTGS2TRPV1MEN1KMT2A | |
| SCHEMBL11080741 | 0.80 | MTNR1A (0.78) | MTNR1AMTNR1BMEN1KMT2APOLB | |
| SCHEMBL28648968 | 0.80 | MEN1 (0.69) | PTGS1PTGS2MEN1KMT2ASIRT1 | |
| SCHEMBL6919750 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1BMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054235-A1 | Benzoheterocyclylethylbenzamide derivatives | BAYER CROPSCIENCE AG (DE) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054235-A1 | Benzoheterocyclylethylbenzamide derivatives | CYP51A1, CBR3, ERG28 | MTNR1A 4329/4885MTNR1B 3409/4885PTGS1 3926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.