SCHEMBL4327271

SCHEMBL4327271

CC1(N=C=O)C(N=C=O)CCCC1(Cc1ccccc1)N=C=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10619983 0.77 MAOA (0.36) MAOAMAOBKDM4E
SCHEMBL10890773 0.72 MAOA (0.41) MAOAMAOB
SCHEMBL7103603 0.71 ALDH1A1 (0.32)
SCHEMBL16701152 0.70 ALDH1A1 (0.31)
SCHEMBL231965 0.69
SCHEMBL10785400 0.68 MAOA (0.40) MAOAMAOBKDM4E
SCHEMBL7553832 0.64 ALDH1A1 (0.34)
SCHEMBL19859474 0.64 ALDH1A1 (0.37)
SCHEMBL9134637 0.62 ALDH1A1 (0.32)
SCHEMBL43172 0.60 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090264551-A1 Photocurable fixture for orthopedic surgery background of the invention ALCARE CO., LTD. 2009-10-22 US disclosed
EP-0370392-A1 Process for the preparation of cyclohexanediisocyanate containing polyisocyanate prepolymers and polyurethanes having high temperature performance AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-05-30 EP disclosed
US-4892920-A ELASTOMERS, CHAIN EXTENSION AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-01-09 US disclosed
EP-0162346-B1 TRIISOCYANATES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE IN THE MANUFACTURE OF POLYURETHANES BAYER AG (DE) 1987-06-03 EP disclosed
US-4603189-A Triisocyanates and a process for their preparation BAYER AKTIENGESELLSCHAFT (DE) 1986-07-29 US disclosed
EP-0162346-A1 Triisocyanates, process for their production, and their use in the manufacture of polyurethanes BAYER AG (DE) 1985-11-27 EP disclosed