Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27841533 | 0.82 | NPC1 (0.44) | MEN1KMT2ATSHRNPC1RAB9A | |
| SCHEMBL4064685 | 0.77 | ALDH1A1 (0.46) | KMT2ATSHRNPC1RAB9ACA12 | |
| SCHEMBL4064579 | 0.77 | NPC1 (0.58) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL3136211 | 0.76 | NPC1 (0.40) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL442434 | 0.75 | MAOB (0.52) | MEN1KMT2ATSHRNPC1RAB9A | |
| SCHEMBL10872465 | 0.74 | TSHR (0.43) | MEN1KMT2ATSHRNPC1RAB9A | |
| SCHEMBL5053649 | 0.73 | TSHR (0.52) | MEN1KMT2AHPGDTSHRNPC1 | |
| SCHEMBL27919356 | 0.71 | ALPI (0.44) | TSHRNPC1RAB9AMAOB | |
| SCHEMBL10872818 | 0.71 | ALDH1A1 (0.44) | MEN1KMT2AHPGDTSHRNPC1 | |
| SCHEMBL3244969 | 0.71 | ALDH1A1 (0.48) | HPGDTSHRALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |