SCHEMBL43277

SCHEMBL43277

O=C(CO)COP(=O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TPI1 P60174 2/20 0.50
PGK1 P00558 1/20 0.38
PGK2 P07205 1/20 0.38
PGD P52209 3/20 0.35
LPAR3 Q9UBY5 3/20 0.33
LPAR1 Q92633 2/20 0.33
LPAR2 Q9HBW0 2/20 0.33
FBP1 P09467 1/20 0.32
FDPS P14324 1/20 0.32
BLM P54132 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28769882 0.97 TPI1 (0.48) TPI1PGK1PGK2PGDLPAR3
Water SCHEMBL28701484 0.97 TPI1 (0.48) TPI1PGK1PGK2PGDLPAR3
SCHEMBL29156118 0.97 TPI1 (0.48) TPI1PGK1PGK2PGDLPAR3
Hydrogen Peroxide SCHEMBL28079410 0.97 TPI1 (0.48) TPI1PGK1PGK2PGDLPAR3
SCHEMBL20798014 0.91 TPI1 (0.43) TPI1PGK1PGK2PGD
SCHEMBL5485133 0.86 TPI1 (0.56) TPI1PGK1PGK2PGDLPAR3
Methylglyoxal SCHEMBL20913196 0.85 TPI1 (0.39) TPI1PGK1PGK2LPAR3LPAR1
SCHEMBL29018985 0.84 TPI1 (0.34) TPI1
SCHEMBL5485138 0.81 MVD (0.47) FDPSBLMTDP1
SCHEMBL2474974 0.79 TPI1 (0.50) TPI1PGK1PGK2PGDLPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6709 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-20260035705-A1 ENGINEERED MICROORGANISMS WITH G3P ->3PG ENZYME AND/OR FRUCTOSE-1,6-BISPHOSPHATASE INCLUDING THOSE HAVING SYNTHETIC OR ENHANCED METHYLOTROPHY AGAIN BIO APS (DK) 2026-02-05 US claimed
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP claimed
US-20250258146-A1 QUANTITATIVE DETECTION METHOD OF MULTIPLE METABOLITES IN BIOLOGICAL SAMPLE AND METABOLIC CHIP HUMAN METABOLOMICS INSTITUTE INC. (CN) 2025-08-14 US claimed
US-20250223617-A1 METHOD FOR SYNTHESIZING POLY(3-HYDROXYBUTYRATE) FROM CRUDE GLYCEROL BY USING ESCHERICHIA COLI AVATACK CO., LTD. (TW) 2025-07-10 US claimed
CN-120060323-A Method for improving methanol utilization capacity of pichia pastoris by over-expressing methanol utilization pathway gene 新苡萃(上海)生物科技有限公司 2025-05-30 CN claimed
CN-119979503-A Mutant protein of dihydroxyacetone phosphate phosphatase and application thereof 中国科学院天津工业生物技术研究所 2025-05-13 CN claimed
CN-119979580-A Method for producing 1, 3-dihydroxyacetone 中国科学院天津工业生物技术研究所 2025-05-13 CN claimed
US-4318980-A Heterogenous specific binding assay employing a cycling reactant as label MILES LABORATORIES, INC. (US) 1982-03-09 US claimed
EP-0035521-A4 METHOD OF DETERMINING A SUBSTRATE IN A SAMPLE. PRINCE CHARLES HOSPITAL DEV CT (AU) 1982-02-16 EP claimed
US-4309502-A ANALYSIS FOR BOTH IN SINGLE CUVETTE BECKMAN INSTRUMENTS, INC. (US) 1982-01-05 US claimed
EP-0035521-A1 METHOD OF DETERMINING A SUBSTRATE IN A SAMPLE THE PRINCE CHARLES HOSPITAL DEVELOPMENT CENTRE TRUST (AU) 1981-09-16 EP claimed
WO-1981000725-A1 METHOD OF DETERMINING A SUBSTRATE IN A SAMPLE CHARLES HOSPITAL DEV (AU) 1981-03-19 WO claimed
US-4245041-A Triglycerides assay and reagents therefor AMERICAN MONITOR CORPORATION (US) 1981-01-13 US claimed
US-4242446-A Method for determining a substance in a biological fluid and reagent combination for use in the method COULTER ELECTRONICS, INC. (US) 1980-12-30 US claimed
US-4209589-A Enzymatic process for preparing [γ-32 P]-labeled nucleotides VANDERBILT UNIVERSITY (US) 1980-06-24 US claimed
US-4151043-A Enzyme determination method SIGMA CHEMICAL COMPANY (US) 1979-04-24 US claimed
US-4001089-A METHOD FOR DETERMINATION OF TRIGLYCERIDES AND GLYCEROL THE DOW CHEMICAL COMPANY (US) 1977-01-04 US claimed