Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPI1 | P60174 | 2/20 | 0.43 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | MVD | P53602 | 1/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43277 | 0.91 | TPI1 (0.50) | TPI1PGK1PGK2PGD | |
| SCHEMBL29018985 | 0.91 | TPI1 (0.34) | TPI1MVDBTN3A1 | |
| SCHEMBL29156118 | 0.89 | TPI1 (0.48) | TPI1PGK1PGK2PGD | |
| Hydrogen Peroxide SCHEMBL28079410 | 0.89 | TPI1 (0.48) | TPI1PGK1PGK2MVDPGD | |
| Water SCHEMBL28701484 | 0.89 | TPI1 (0.48) | TPI1PGK1PGK2BTN3A1PGD | |
| SCHEMBL28769882 | 0.89 | TPI1 (0.48) | TPI1PGK1PGK2PGD | |
| SCHEMBL5485133 | 0.83 | TPI1 (0.56) | TPI1PGK1PGK2PGD | |
| SCHEMBL5485138 | 0.83 | MVD (0.47) | MVDBTN3A1 | |
| SCHEMBL10876378 | 0.79 | MVD (0.45) | MVDBTN3A1 | |
| SCHEMBL15150489 | 0.78 | PLA2G2A (0.34) | TPI1MVDBTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116087486-B | Biomarkers for early prediction of cardiovascular disease (CVD) in diabetics and uses thereof | 中国医学科学院阜外医院 | 2024-02-02 | — | — | CN | disclosed |
| CN-116087485-B | Biomarkers for early prediction of cardiovascular disease (CVD) in diabetics and uses thereof | 中国医学科学院阜外医院 | 2023-10-20 | — | — | CN | disclosed |
| CN-116087488-A | Biomarkers for early prediction of cardiovascular disease (CVD) in diabetics and uses thereof | 中国医学科学院阜外医院 | 2023-05-09 | — | — | CN | disclosed |
| CN-116087487-A | Biomarkers for early prediction of cardiovascular disease (CVD) in diabetics and uses thereof | 中国医学科学院阜外医院 | 2023-05-09 | — | — | CN | disclosed |
| CN-116087486-A | Biomarkers for early prediction of cardiovascular disease (CVD) in diabetics and uses thereof | 中国医学科学院阜外医院 | 2023-05-09 | — | — | CN | disclosed |
| CN-116087489-A | Biomarkers for early prediction of cardiovascular disease (CVD) in diabetics and uses thereof | 中国医学科学院阜外医院 | 2023-05-09 | — | — | CN | disclosed |
| CN-116087485-A | Biomarkers for early prediction of cardiovascular disease (CVD) in diabetics and uses thereof | 中国医学科学院阜外医院 | 2023-05-09 | — | — | CN | disclosed |
| EP-3679065-A1 | SIGNALING AND ANTIGEN-PRESENTING BIFUNCTIONAL RECEPTORS (SABR) | California Institute of Technology (US) | 2020-07-15 | — | — | EP | disclosed |
| WO-2019051001-A1 | SIGNALING AND ANTIGEN-PRESENTING BIFUNCTIONAL RECEPTORS (SABR) | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-03-14 | — | — | WO | disclosed |