Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330122 | 0.82 | KMT2A (0.47) | KMT2AMEN1TRPV1NPC1RAB9A | |
| SCHEMBL2575239 | 0.77 | TRPV1 (0.40) | KMT2AMEN1TRPV1ALDH1A1CYP1A2 | |
| SCHEMBL895941 | 0.74 | KMT2A (0.55) | KMT2AMEN1NPSR1ALDH1A1CYP1A2 | |
| SCHEMBL11131276 | 0.72 | LIPE (0.46) | KMT2AMEN1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL10424370 | 0.71 | NPC1 (0.57) | KMT2AMEN1TRPV1NPC1RAB9A | |
| SCHEMBL2397057 | 0.71 | PIK3CD (0.46) | KMT2AMEN1TRPV1NPC1RAB9A | |
| SCHEMBL2560126 | 0.71 | MEN1 (0.46) | KMT2AMEN1TRPV1NPSR1CYP1A2 | |
| SCHEMBL1641651 | 0.70 | KMT2A (0.55) | KMT2AMEN1TRPV1NPC1RAB9A | |
| SCHEMBL8154848 | 0.70 | TRPV1 (0.66) | KMT2AMEN1TRPV1NPC1RAB9A | |
| SCHEMBL27594823 | 0.70 | MAPK1 (0.51) | KMT2AMEN1NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |