Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4328145 | 0.82 | KMT2A (0.44) | KMT2AMEN1TRPV1NPSR1NPC1 | |
| SCHEMBL4454936 | 0.81 | ABCB1 (0.40) | KMT2AMEN1NPSR1ALDH1A1MAPT | |
| SCHEMBL896877 | 0.77 | ALDH1A1 (0.59) | KMT2AMEN1NPSR1RAB9AALDH1A1 | |
| SCHEMBL10424370 | 0.74 | NPC1 (0.57) | KMT2AMEN1TRPV1NPSR1NPC1 | |
| SCHEMBL8154848 | 0.73 | TRPV1 (0.66) | KMT2AMEN1TRPV1NPSR1NPC1 | |
| SCHEMBL1641651 | 0.73 | KMT2A (0.55) | KMT2AMEN1TRPV1NPSR1NPC1 | |
| SCHEMBL22543183 | 0.72 | MALT1 (0.47) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL896526 | 0.72 | ALDH1A1 (0.50) | KMT2AMEN1NPSR1ALDH1A1CYP1A2 | |
| SCHEMBL896116 | 0.72 | NPC1 (0.54) | KMT2AMEN1TRPV1NPSR1NPC1 | |
| SCHEMBL896310 | 0.72 | SMN1; SMN2 (0.57) | KMT2AMEN1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |