Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10526220 | 1.00 | ACHE (0.62) | ACHEHPGDLMNATSHRNFE2L2 | |
| SCHEMBL19010398 | 0.92 | ACHE (0.52) | ACHEHPGDLMNATSHRNFE2L2 | |
| SCHEMBL262688 | 0.87 | HPGD (0.65) | ACHEHPGDLMNATSHRGAA | |
| SCHEMBL5435185 | 0.87 | HPGD (0.65) | ACHEHPGDLMNATSHRGAA | |
| SCHEMBL779999 | 0.87 | CES2 (0.39) | ACHELMNA | |
| SCHEMBL9927352 | 0.87 | CES2 (0.39) | ACHELMNA | |
| SCHEMBL6626629 | 0.85 | HPGD (0.62) | ACHEHPGDLMNATSHRGAA | |
| Hydrogen Peroxide SCHEMBL8672187 | 0.82 | BCL2L1 (0.46) | LMNAKMT2AMEN1 | |
| SCHEMBL11991140 | 0.82 | BCL2L1 (0.46) | ACHELMNATSHRSMN1; SMN2 | |
| Hydrogen Peroxide SCHEMBL8672190 | 0.82 | BCL2L1 (0.46) | LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635744-B2 | Trifluorovinyloxy monomers and polymers | GENERAL ELECTRIC COMPANY (US) | 2009-12-22 | — | — | US | disclosed |
| US-20070238856-A1 | Trifluorovinyloxy monomers and polymers | GENERAL ELECTRIC COMPANY | 2007-10-11 | — | — | US | disclosed |
| US-4847419-A | Process for the preparation of bifunctional tertiary aromatic phosphine sulfides, and also several specific representatives of this class of compounds | HOECHST AKTIENGESELL (DE) | 1989-07-11 | — | — | US | disclosed |