SCHEMBL4328369

SCHEMBL4328369

C=C[Si](C)(C=C)O[Si](C)(C)C.c1ccc2c(c1)CC2.c1ccc2c(c1)CC2

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
CYP2A6 P11509 1/20 0.32
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31
DRD2 P14416 1/20 0.31
DRD1 P21728 1/20 0.31
DRD4 P21917 1/20 0.31
DRD5 P21918 1/20 0.31
DRD3 P35462 1/20 0.31
HTR2C P28335 1/20 0.31
SETD7 Q8WTS6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6037078 1.00 TSHR (0.34) TSHRCYP2A6MAOAMAOBDRD2
SCHEMBL5485162 0.82
Toluene SCHEMBL28145641 0.78 TSHR (0.44) TSHR
SCHEMBL599315 0.78
SCHEMBL17082 0.76
SCHEMBL5488203 0.76
SCHEMBL115208 0.73
SCHEMBL3065380 0.73
SCHEMBL16401966 0.73
SCHEMBL6050879 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5585450-A PHOTODEFINABLE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-12-17 US claimed
EP-0616701-A4 PHOTOCURABLE CYCLOBUTARENE COMPOSITIONS. DOW CHEMICAL CO (US) 1995-06-14 EP claimed
EP-0616701-A1 PHOTOCURABLE CYCLOBUTARENE COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1994-09-28 EP claimed
WO-1993012055-A2 PHOTOCURABLE CYCLOBUTARENE COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1993-06-24 WO claimed
US-20150221896-A1 AMBIPOLAR, LIGHT-EMITTING FIELD-EFFECT TRANSISTORS CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) 2015-08-06 US disclosed
EP-1704587-B1 N-CHANNEL TRANSISTOR CAMBRIDGE ENTPR LTD (GB) 2015-02-11 EP disclosed
EP-1990845-B1 Ambipolar, light-emitting field-effect transistors CAMBRIDGE ENTPR LTD (GB) 2012-10-24 EP disclosed
US-7638793-B2 N-channel transistor CAMBRIDGE ENTERPRISE LTD (GB) 2009-12-29 US disclosed
EP-1990845-A1 Ambipolar, light-emitting field-effect transistors Cambridge Enterprise Limited (GB) 2008-11-12 EP disclosed
EP-1711970-B1 AMBIPOLAR, LIGHT-EMITTING FIELD-EFFECT TRANSISTORS CAMBRIDGE ENTPR LTD (GB) 2008-09-03 EP disclosed
US-20070295955-A1 N-Channel Transistor CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED 2007-12-27 US disclosed
US-20070278478-A1 Ambipolar, Light-Emitting Field-Effect Transistors PLASTIC LOGIC LIMITED (GB) 2007-12-06 US disclosed
US-5585450-A PHOTODEFINABLE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-12-17 US disclosed
EP-0616701-A4 PHOTOCURABLE CYCLOBUTARENE COMPOSITIONS. DOW CHEMICAL CO (US) 1995-06-14 EP disclosed
EP-0616701-A4 PHOTOCURABLE CYCLOBUTARENE COMPOSITIONS. DOW CHEMICAL CO (US) 1995-06-14 EP disclosed
EP-0616701-A1 PHOTOCURABLE CYCLOBUTARENE COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1994-09-28 EP disclosed
EP-0616701-A1 PHOTOCURABLE CYCLOBUTARENE COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1994-09-28 EP disclosed
WO-1993012055-A3 PHOTOCURABLE CYCLOBUTARENE COMPOSITIONS DOW CHEMICAL CO (US) 1993-08-05 WO disclosed
WO-1993012055-A2 PHOTOCURABLE CYCLOBUTARENE COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1993-06-24 WO disclosed
WO-1993012055-A2 PHOTOCURABLE CYCLOBUTARENE COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1993-06-24 WO disclosed