Toluene

Toluene

SCHEMBL28145641

C=C[Si](C)(C=C)O[Si](C)(C)C.Cc1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
LMNA P02545 1/20 0.44
ALOX12 P18054 1/20 0.44
ACHE P22303 1/20 0.44
NPC1 O15118 4/20 0.33
RAB9A P51151 4/20 0.33
HPGD P15428 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NFKB1 P19838 2/20 0.33
NFKB2 Q00653 2/20 0.33
RELA Q04206 2/20 0.33
POLB P06746 1/20 0.33
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MMP1 P03956 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599315 0.84
SCHEMBL5485162 0.83
Toluene SCHEMBL11435719 0.80 ACHE (0.61) TSHRLMNAALOX12ACHENPC1
SCHEMBL4328369 0.78 TSHR (0.34) TSHR
SCHEMBL6037078 0.78 TSHR (0.34) TSHR
SCHEMBL17082 0.78
SCHEMBL1928067 0.77 ESR1 (0.31)
SCHEMBL5488203 0.77
SCHEMBL4867196 0.77 ESR1 (0.31)
SCHEMBL16401966 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109913596-A A kind of Leather mildew-proof antibacterial agent and preparation method thereof 汪逸凡 2019-06-21 CN claimed
CN-106633782-A Heat-conductive fluorinated curable composition, cured product thereof, and electric/electronic part 信越化学工业株式会社 2017-05-10 CN disclosed