Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4323474 | 1.00 | HPGD (0.44) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4323776 | 1.00 | HPGD (0.44) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4323703 | 1.00 | HPGD (0.44) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9846515 | 0.87 | HPGD (0.37) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10465894 | 0.87 | HPGD (0.37) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9522886 | 0.84 | PTGER1 (0.42) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8791943 | 0.83 | HPGD (0.42) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28814775 | 0.83 | RAB9A (0.41) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7760354 | 0.83 | RAB9A (0.41) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28814793 | 0.83 | RAB9A (0.41) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144263-A2 | PROCESS FOR OBTAINING 4-HYDROXY-6-METHYL-5, 6-DIHYDRO-4H-THIENO [2,3-b] THIOPYRAN-7, 7-DIOXIDE AND ITS ENANTIOMERS, AND APPLICATIONS THEREOF | RAGACTIVES, S.L.U. (ES) | 2009-12-03 | — | — | WO | claimed |
| EP-2128161-A1 | Process for obtaining 4-hydroxy-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-7,7-dioxide and its enantiomers, and applications thereof | Ragactives, S.L. (ES) | 2009-12-02 | — | — | EP | claimed |
| CN-114891838-A | Synthesis method of dorzolamide hydrochloride intermediate (S) -3- (2-thiophenylthio) -butyric acid | 株洲壹诺生物技术有限公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2009144263-A2 | PROCESS FOR OBTAINING 4-HYDROXY-6-METHYL-5, 6-DIHYDRO-4H-THIENO [2,3-b] THIOPYRAN-7, 7-DIOXIDE AND ITS ENANTIOMERS, AND APPLICATIONS THEREOF | RAGACTIVES, S.L.U. (ES) | 2009-12-03 | — | — | WO | disclosed |
| EP-2128161-A1 | Process for obtaining 4-hydroxy-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-7,7-dioxide and its enantiomers, and applications thereof | Ragactives, S.L. (ES) | 2009-12-02 | — | — | EP | disclosed |