Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28814793 | 1.00 | RAB9A (0.41) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7760354 | 1.00 | RAB9A (0.41) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4323703 | 0.83 | HPGD (0.44) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4323474 | 0.83 | HPGD (0.44) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4323776 | 0.83 | HPGD (0.44) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4328403 | 0.83 | HPGD (0.44) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3927048 | 0.81 | GAA (0.39) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9846643 | 0.81 | ALDH1A1 (0.41) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4790745 | 0.81 | ALDH1A1 (0.41) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9106592 | 0.80 | TAS1R3 (0.38) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114891838-A | Synthesis method of dorzolamide hydrochloride intermediate (S) -3- (2-thiophenylthio) -butyric acid | 株洲壹诺生物技术有限公司 | 2022-08-12 | — | — | CN | disclosed |