Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 5/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25728687 | 0.87 | MAOA (0.68) | MAOAMAOBSLC6A4LMNAPOLB | |
| SCHEMBL30101701 | 0.86 | MAOA (0.57) | MAOAMAOBSLC6A4LMNAPOLB | |
| SCHEMBL13928826 | 0.79 | MAOA (0.51) | MAOAMAOBSLC6A4LMNAPOLB | |
| SCHEMBL11081316 | 0.78 | MAOA (0.59) | MAOAMAOBSLC6A4CYP2D6CYP1A2 | |
| Bromide SCHEMBL11167461 | 0.78 | MAOA (0.53) | MAOAMAOBSLC6A4LMNAPOLB | |
| SCHEMBL30634713 | 0.77 | MAOB (1.00) | MAOAMAOBSLC6A4DRD1DRD4 | |
| SCHEMBL5525085 | 0.77 | MAOB (1.00) | MAOAMAOBSLC6A4DRD1DRD4 | |
| Hydrochloric Acid SCHEMBL10915875 | 0.77 | MAOA (0.57) | MAOAMAOBSLC6A4CYP2D6CYP1A2 | |
| SCHEMBL27624815 | 0.76 | ABCB1 (0.67) | LMNAPOLBTDP1DRD1 | |
| SCHEMBL27644926 | 0.76 | ABCB1 (0.67) | LMNAPOLBTDP1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |