SCHEMBL30101701

SCHEMBL30101701

COc1cc2c(c(O)c1OC)CN(C)CC2

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.57
MAOB P27338 2/20 0.57
SLC6A4 P31645 1/20 0.57
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
TDP1 Q9NUW8 2/20 0.49
LMNA P02545 1/20 0.49
POLB P06746 1/20 0.49
BCHE P06276 1/20 0.48
DRD1 P21728 2/20 0.47
DRD4 P21917 1/20 0.47
DRD5 P21918 1/20 0.47
DRD2 P14416 1/20 0.45
CCNB2 O95067 1/20 0.45
CDK1 P06493 1/20 0.45
CCNB1 P14635 1/20 0.45
CCNB3 Q8WWL7 1/20 0.45
ACHE P22303 1/20 0.44
ATM Q13315 1/20 0.44
CA2 P00918 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4328518 0.86 MAOA (0.62) MAOAMAOBSLC6A4CYP1A2CYP2D6
SCHEMBL25728687 0.77 MAOA (0.68) MAOAMAOBSLC6A4CYP1A2CYP2D6
SCHEMBL13928826 0.75 MAOA (0.51) MAOAMAOBSLC6A4CYP1A2CYP2D6
SCHEMBL11081316 0.74 MAOA (0.59) MAOAMAOBSLC6A4CYP1A2CYP2D6
Bromide SCHEMBL11167461 0.74 MAOA (0.53) MAOAMAOBSLC6A4CYP1A2CYP2D6
SCHEMBL24277006 0.74 DRD2 (0.47) MAOAMAOBSLC6A4DRD1DRD4
SCHEMBL22680369 0.73 MAPT (0.48) MAOAMAOBSLC6A4CYP1A2CYP2D6
SCHEMBL30634713 0.73 MAOB (1.00) MAOAMAOBSLC6A4DRD1DRD4
SCHEMBL5525085 0.73 MAOB (1.00) MAOAMAOBSLC6A4DRD1DRD4
SCHEMBL20683185 0.73 MAOA (0.77) MAOAMAOBSLC6A4DRD1DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260053878-A1 PROCESS FOR EXTRACTION OF ACTIVE COMPOUNDS FROM PLANT BIOMASS NEURAL THERAPEUTICS INC (CA) 2026-02-26 US disclosed
US-12551519-B2 Extraction system and method for organic metabolites VCENNA TECH & LABS INC (CA) 2026-02-17 US disclosed
US-20250162980-A1 METHODS FOR PREPARING MESCALINE JOURNEY COLAB CORP. 2025-05-22 US disclosed
US-20240245632-A1 METHODS OF TREATING SUBSTANCE USE DISORDERS USING MESCALINE JOURNEY COLAB CORP. 2024-07-25 US disclosed
US-20240123005-A1 EXTRACTION SYSTEM AND METHOD FOR ORGANIC METABOLITES Etminan, Seyed Reza (CA) 2024-04-18 US disclosed
WO-2024040358-A1 PROCESS FOR EXTRACTION OF ACTIVE COMPOUNDS FROM PLANT BIOMASS NEURAL THERAPEUTICS INC. (CA) 2024-02-29 WO disclosed
WO-2023164178-A2 METHODS FOR PREPARING MESCALINE JOURNEY COLAB CORP. (US) 2023-08-31 WO disclosed
WO-2022251690-A1 MESCALINE FOR THE TREATMENT OF SUBSTANCE USE DISORDERS JOURNEY COLAB CORP. (US) 2022-12-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053878-A1 PROCESS FOR EXTRACTION OF ACTIVE COMPOUNDS FROM PLANT BIOMASS CARM1, CLK4, NPM1 MAOA 3965/4885MAOB 3868/4885SLC6A4 4821/4885
US-20240245632-A1 METHODS OF TREATING SUBSTANCE USE DISORDERS USING MESCALINE SLC6A12, SLC6A3, TPMT MAOA 364/4885MAOB 320/4885SLC6A4 7/4885
US-20250162980-A1 METHODS FOR PREPARING MESCALINE IL4I1, ME3, LIG3 MAOA 1620/4885MAOB 1420/4885SLC6A4 309/4885
US-12551519-B2 Extraction system and method for organic metabolites SHH, WNT1, WNT3A MAOA 558/4885MAOB 640/4885SLC6A4 2869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.