Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5599521 | 0.84 | GPBAR1 (0.31) | GPBAR1 | |
| Hydrochloric Acid SCHEMBL6352586 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL3900300 | 0.78 | — | — | |
| SCHEMBL3967802 | 0.69 | CFTR (0.33) | — | |
| SCHEMBL4468810 | 0.69 | CFTR (0.33) | — | |
| SCHEMBL24516482 | 0.60 | SLC6A2 (0.42) | — | |
| SCHEMBL27730156 | 0.57 | CFTR (0.32) | — | |
| SCHEMBL24947816 | 0.56 | ACHE (0.33) | — | |
| SCHEMBL19240294 | 0.56 | CYP19A1 (0.38) | — | |
| SCHEMBL13821949 | 0.56 | SLC6A2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485686-B2 | Manufacturing method of polyolefin | JAPAN POLYPROPYLENE CORPORATION (JP) | 2009-02-03 | — | — | US | disclosed |
| US-20070082185-A1 | Multi-layered film | JAPAN POLYPROPYLENE CORPORATION (JP) | 2007-04-12 | — | — | US | disclosed |