Toluene

Toluene

SCHEMBL4328611

CCOC(=O)C=[N+]=[N-].Cc1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 6/20 0.42
TSHR P16473 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
LMNA P02545 3/20 0.40
MDM2 Q00987 2/20 0.40
MDM4 O15151 1/20 0.40
ALDH1A1 P00352 1/20 0.40
THRB P10828 1/20 0.40
PIN1 Q13526 2/20 0.39
GAA P10253 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPK1 P28482 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL28512915 0.88 CYP1A2 (0.44) CYP1A2CYP2C9CYP2C19MEN1KMT2A
SCHEMBL4412 0.84
Acetic Acid SCHEMBL28563384 0.82 HCAR2 (0.47) CYP1A2CYP2C9CYP2C19MEN1KMT2A
SCHEMBL28285089 0.82
Alcohol SCHEMBL28357108 0.80 HCAR2 (0.43) CYP1A2CYP2C9CYP2C19MAPTNPSR1
Toluene SCHEMBL1396212 0.79 MEN1 (0.49) MEN1KMT2AMAPTTSHRLMNA
Methylene Chloride SCHEMBL27697374 0.78 HCAR2 (0.42) CYP1A2CYP2C9CYP2C19MAPTNPSR1
SCHEMBL27338823 0.78 MGLL (0.53) MAPTTSHRNPSR1LMNAALDH1A1
Acrylic Acid Ethyl Ester SCHEMBL7116609 0.77 THRB (0.53) MEN1KMT2AMAPTTSHRLMNA
1,2-Dichloroethane SCHEMBL28431339 0.77 HCAR2 (0.41) CYP1A2CYP2C9CYP2C19MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114206901-B Process for producing peptide compound 日产化学株式会社 2024-02-20 CN disclosed
WO-2023163140-A1 INDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF 日本たばこ産業株式会社 2023-08-31 WO disclosed
CN-114206901-A Method for producing peptide compound 日产化学株式会社 2022-03-18 CN disclosed
WO-2021039901-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND 日産化学株式会社 2021-03-04 WO disclosed
WO-2009141412-A1 1,6-DISUBSTITUTED 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES FOR USE AS TRIPLE REUPTAKE INHIBITORS GLAXO GROUP LIMITED (GB) 2009-11-26 WO disclosed