SCHEMBL4329328

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4332113	0.88	KDM4E (0.52)	RECQLTSHRALDH1A1USP2NPSR1
	SCHEMBL4341451	0.87	KDM4E (0.49)	RECQLTSHRALDH1A1USP2NPSR1
	SCHEMBL4338790	0.84	RECQL (0.48)	RECQLCYP1A2CYP3A4TSHRBLM
	SCHEMBL2870798	0.84	NTRK1 (0.52)	CYP1A2CYP3A4TSHRBLML3MBTL1
	SCHEMBL4340974	0.83	NTRK1 (0.49)	MAPK1NTRK1
	SCHEMBL4329145	0.82	HPGD (0.48)	TSHRALDH1A1USP2NPSR1POLB
	SCHEMBL4335912	0.81	CDK9 (0.49)	MAPK1NTRK1ROCK2NAMPT
	SCHEMBL2862186	0.80	SMN1; SMN2 (0.56)	HCRTR1HCRTR2MAPK1TP53MAPT
	SCHEMBL2864643	0.80	SMN1; SMN2 (0.56)	CYP3A4HCRTR1HCRTR2MAPK1TP53
	SCHEMBL2863001	0.79	NTRK1 (0.56)	MAPK1NTRK1ROCK2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.