SCHEMBL2870798

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2863001	0.92	NTRK1 (0.56)	NTRK1DGAT2MAPK1CSNK1DROCK2
	SCHEMBL13198265	0.90	NTRK1 (0.51)	NTRK1DGAT2MAPK1CSNK1DHCRTR1
	SCHEMBL2872610	0.89	DGAT2 (0.56)	NTRK1DGAT2MAPK1CSNK1DROCK2
	SCHEMBL2867437	0.88	CSNK1D (0.47)	DGAT2MAPK1CSNK1DKMT2A
	SCHEMBL2870225	0.85	NTRK1 (0.50)	NTRK1DGAT2MAPK1CSNK1DALDH1A1
	SCHEMBL4329328	0.84	RECQL (0.60)	NTRK1MAPK1HCRTR1HCRTR2L3MBTL1
	SCHEMBL13198273	0.82	DGAT2 (0.50)	NTRK1DGAT2MAPK1CSNK1DROCK2
	SCHEMBL2862635	0.80	DGAT2 (0.56)	NTRK1DGAT2CSNK1DROCK2ROCK1
	SCHEMBL2863237	0.79	CSNK1D (0.52)	NTRK1DGAT2MAPK1CSNK1DROCK2
	SCHEMBL4335912	0.77	CDK9 (0.49)	NTRK1MAPK1ROCK2PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.