SCHEMBL4329591

SCHEMBL4329591

CO[C@H]1O[C@@H](C=S)[C@H](O)[C@@H](O)[C@H]1O

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
M6PR P20645 2/20 0.51
G6PD P11413 4/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SLC5A2 P31639 4/20 0.32
SYNJ2 O15056 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16098706 1.00 M6PR (0.51) M6PRG6PDMEN1KMT2ASLC5A2
SCHEMBL16093664 1.00 M6PR (0.51) M6PRG6PDMEN1KMT2ASLC5A2
SCHEMBL15698043 0.79 M6PR (0.56) M6PRG6PDSYNJ2
SCHEMBL15700171 0.79 M6PR (0.56) M6PRG6PDSYNJ2
SCHEMBL19502333 0.79 M6PR (0.56) M6PRG6PDSYNJ2
SCHEMBL8615533 0.79 M6PR (0.56) M6PRG6PDSYNJ2
SCHEMBL20143964 0.79 M6PR (0.56) M6PRG6PDSYNJ2
SCHEMBL13072839 0.77 M6PR (0.46) M6PRG6PDMEN1KMT2ASYNJ2
SCHEMBL13929525 0.77 M6PR (0.46) M6PRG6PDMEN1KMT2ASYNJ2
SCHEMBL220693 0.74 M6PR (0.42) M6PRG6PDMEN1KMT2ASYNJ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170281772-A1 A NEURAL SUBSTRATE FOR SUGAR PREFERENCE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2017-10-05 US claimed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed
US-20170281772-A1 A NEURAL SUBSTRATE FOR SUGAR PREFERENCE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2017-10-05 US disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 EP disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 EP disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 WO disclosed