SCHEMBL220693

SCHEMBL220693

COC1OC(OC)C(O)C1O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
M6PR P20645 2/20 0.42
SYNJ2 O15056 1/20 0.40
G6PD P11413 3/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
LGALS8 O00214 2/20 0.36
MGAM O43451 4/20 0.34
SI P14410 4/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13072839 0.97 M6PR (0.46) M6PRSYNJ2G6PDMEN1KMT2A
SCHEMBL13929525 0.97 M6PR (0.46) M6PRSYNJ2G6PDMEN1KMT2A
SCHEMBL12020014 0.87 M6PR (0.37) M6PRSYNJ2G6PDMEN1KMT2A
SCHEMBL18023863 0.85 M6PR (0.39) M6PRSYNJ2G6PDMEN1KMT2A
SCHEMBL12020066 0.85 LGALS8 (0.41) M6PRSYNJ2G6PDMEN1KMT2A
SCHEMBL13126787 0.85 M6PR (0.39) M6PRSYNJ2G6PDMEN1KMT2A
SCHEMBL8273427 0.84 M6PR (0.40) M6PRSYNJ2G6PDMEN1KMT2A
SCHEMBL7208934 0.83 M6PR (0.42) M6PRSYNJ2G6PDMEN1KMT2A
SCHEMBL10231826 0.83 M6PR (0.42) M6PRSYNJ2G6PDMEN1KMT2A
SCHEMBL12820024 0.83 M6PR (0.42) M6PRSYNJ2G6PDLGALS8MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118515987-A Functionalized hollow glass microsphere and preparation method thereof 达州亮博新材料科技有限公司 2024-08-20 CN claimed
US-7728001-B2 Opioid receptor ligands and methods for their preparation UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2010-06-01 US claimed
CN-118515987-A Functionalized hollow glass microsphere and preparation method thereof 达州亮博新材料科技有限公司 2024-08-20 CN disclosed
CN-118515987-A Functionalized hollow glass microsphere and preparation method thereof 达州亮博新材料科技有限公司 2024-08-20 CN disclosed
US-9428494-B2 Therapeutic compounds UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2016-08-30 US disclosed
CN-103911674-A CELLULOSE CROSSLINKED FIBERS MANUFACTURED FROM PLASMA TREATED PULP WEYERHAEUSER NR CO 2014-07-09 CN disclosed
CN-102312384-B Reduction of fiber knots of cellulose crosslinked fibers by using plasma pre-treated pulpsheets WEYERHAEUSER NR CO 2014-03-26 CN disclosed
US-8475631-B2 Reduction of fiber knots of cellulose crosslinked fibers by using plasma pre-treated pulpsheets Wyerhauser NR Company (US) 2013-07-02 US disclosed
US-20130137862-A1 CELLULOSE CROSSLINKED FIBERS MANUFACTURED FROM PLASMA TREATED PULP WEYERHAEUSER NR COMPANY (US) 2013-05-30 US disclosed
CN-102312383-A Tie the cellulose crosslinked fiber that reduces from the fiber of plasma treated pulp sheet production WEYERHAEUSER NR CO 2012-01-11 CN disclosed
CN-102312384-A Use the pretreated pulp sheet material of plasma to reduce the fiber knot of cellulose crosslinked fiber WEYERHAEUSER NR CO 2012-01-11 CN disclosed
US-20120004406-A1 CELLULOSE CROSSLINKED FIBERS WITH REDUCED FIBER KNOTS MANUFACTURED FROM PLASMA TREATED PULPSHEETS WEYERHAEUSER NR COMPANY (US) 2012-01-05 US disclosed
US-20120000618-A1 REDUCTION OF FIBER KNOTS OF CELLULOSE CROSSLINKED FIBERS BY USING PLASMA PRE-TREATED PULPSHEETS WEYERHAEUSER NR COMPANY (US) 2012-01-05 US disclosed
US-20100179217-A1 THERAPEUTIC COMPOUNDS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2010-07-15 US disclosed
US-7728001-B2 Opioid receptor ligands and methods for their preparation UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2010-06-01 US disclosed
WO-2008055261-A2 THERAPEUTIC COMPOUNDS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2008-05-08 WO disclosed
WO-2006031782-A2 SALVINORIN DERIVATIVES AS OPIOID RECEPTOR LIGANDS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2006-03-23 WO disclosed
US-20060058264-A1 Opioid receptor ligands and methods for their preparation THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2006-03-16 US disclosed
US-4900324-A HYDROXY ACETAL CELLULOSE CROSSLINKING AGENTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1990-02-13 US disclosed
US-4900324-A HYDROXY ACETAL CELLULOSE CROSSLINKING AGENTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1990-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100179217-A1 THERAPEUTIC COMPOUNDS OPRL1, OPRK1, OPRM1 M6PR 288/4885SYNJ2 3325/4885G6PD 4018/4885
US-20060058264-A1 Opioid receptor ligands and methods for their preparation OPRL1, OPRM1, OPRK1 M6PR 125/4885SYNJ2 4477/4885G6PD 4372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.