Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 3/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1790289 | 0.82 | F2 (0.56) | F2PRSS1PRSS2PRSS3HTR6 | |
| SCHEMBL29723528 | 0.82 | F2 (0.56) | F2PRSS1PRSS2PRSS3HTR6 | |
| SCHEMBL30286769 | 0.79 | F2 (0.56) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL875072 | 0.79 | F2 (0.56) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL180705 | 0.77 | F2 (0.43) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL5401910 | 0.76 | CA1 (0.43) | F2PRSS1PRSS2PRSS3HTR6 | |
| SCHEMBL4329198 | 0.75 | CA1 (0.35) | CA1CA2CA9 | |
| SCHEMBL26603542 | 0.74 | ALDH1A1 (0.44) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL10616438 | 0.72 | GAA (0.34) | F2PRSS1PRSS2PRSS3HTR6 | |
| SCHEMBL183894 | 0.72 | F2 (0.37) | F2PRSS1PRSS2PRSS3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4344471-B2 | — | — | 2009-10-14 | — | — | JP | claimed |
| JP-2001514289-A | — | — | 2001-09-11 | — | — | JP | claimed |
| JP-2001514288-A | — | — | 2001-09-11 | — | — | JP | claimed |
| JP-2001514287-A | — | — | 2001-09-11 | — | — | JP | claimed |
| EP-1007585-A1 | RHEOLOGY MODIFICATION OF INTERPOLYMERS OF ALPHA-OLEFINS AND VINYL AROMATIC MONOMERS | THE DOW CHEMICAL COMPANY (US) | 2000-06-14 | — | — | EP | claimed |
| EP-1007586-A1 | RHEOLOGY MODIFICATION OF LOW DENSITY POLYETHYLENE | THE DOW CHEMICAL COMPANY (US) | 2000-06-14 | — | — | EP | claimed |
| EP-1007587-A1 | RHEOLOGY MODIFICATION OF ELASTOMERS | THE DOW CHEMICAL COMPANY (US) | 2000-06-14 | — | — | EP | claimed |
| WO-1999010423-A1 | RHEOLOGY MODIFICATION OF ELASTOMERS | THE DOW CHEMICAL COMPANY (US) | 1999-03-04 | — | — | WO | claimed |
| WO-1999010422-A1 | RHEOLOGY MODIFICATION OF LOW DENSITY POLYETHYLENE | THE DOW CHEMICAL COMPANY (US) | 1999-03-04 | — | — | WO | claimed |
| WO-1999010421-A1 | RHEOLOGY MODIFICATION OF INTERPOLYMERS OF ALPHA-OLEFINS AND VINYL AROMATIC MONOMERS | THE DOW CHEMICAL COMPANY (US) | 1999-03-04 | — | — | WO | claimed |
| EP-1263873-A2 | POLYOLEFIN COMPOSITION WITH IMPROVED IMPACT PROPERTIES | THE DOW CHEMICAL COMPANY (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2000078858-A2 | POLYOLEFIN COMPOSITION WITH IMPROVED IMPACT PROPERTIES | THE DOW CHEMICAL COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |