SCHEMBL180705

SCHEMBL180705

[N-]=[N+]=NS(=O)(=O)c1ccc2ccc(S(=O)(=O)N=[N+]=[N-])cc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 3/20 0.43
PRSS1 P07477 3/20 0.43
PRSS2 P07478 3/20 0.43
PRSS3 P35030 3/20 0.43
LMNA P02545 2/20 0.38
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
CA5A P35218 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
MCOLN3 Q8TDD5 2/20 0.32
TSHR P16473 2/20 0.32
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30286769 0.91 F2 (0.56) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL875072 0.91 F2 (0.56) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL10823807 0.83 CA1 (0.43) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL5401910 0.79 CA1 (0.43) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL4329198 0.78 CA1 (0.35) CA1CA2CA9CA5ACA5B
SCHEMBL17704473 0.78 NPY5R (0.44) F2PRSS1PRSS2PRSS3CA1
SCHEMBL5676376 0.77 CA2 (0.41) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL4329660 0.77 F2 (0.39) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL10829353 0.74 LMNA (0.44) F2PRSS1PRSS2PRSS3LMNA
SCHEMBL6654348 0.74 CA1 (0.39) F2PRSS1PRSS2PRSS3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8436089-B2 Polypropylene composition, a method of producing the same, and articles made therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2013-05-07 US claimed
EP-2142596-B1 A POLYPROPYLENE COMPOSITION, A METHOD OF PRODUCING THE SAME, AND ARTICLES MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2011-10-26 EP claimed
EP-1658623-B1 CABLE INSULATION COMPOSITIONS WITH ENHANCED RHEOLOGY AND PROCESSABILITY DOW GLOBAL TECHNOLOGIES INC (US) 2010-09-29 EP claimed
JP-2010523762-A 2010-07-15 JP claimed
US-20100048792-A1 A POLYPROPYLENE COMPOSITION, A METHOD OF PRODUCING THE SAME, AND ARTICLES MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC 2010-02-25 US claimed
EP-2142596-A1 A POLYPROPYLENE COMPOSITION, A METHOD OF PRODUCING THE SAME, AND ARTICLES MADE THEREFROM Dow Global Technologies Inc. (US) 2010-01-13 EP claimed
JP-4342721-B2 2009-10-14 JP claimed
WO-2008121464-A1 A POLYPROPYLENE COMPOSITION, A METHOD OF PRODUCING THE SAME, AND ARTICLES MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2008-10-09 WO claimed
EP-1007587-B1 RHEOLOGY MODIFICATION OF ELASTOMERS DOW GLOBAL TECHNOLOGIES INC (US) 2006-04-05 EP claimed
EP-1157066-B1 PROCESS FOR PREPARING THERMOPLASTIC VULCANIZATES DOW GLOBAL TECHNOLOGIES INC (US) 2006-01-25 EP claimed
EP-1157066-A1 PROCESS FOR PREPARING THERMOPLASTIC VULCANIZATES THE DOW CHEMICAL COMPANY (US) 2001-11-28 EP claimed
JP-2001514293-A 2001-09-11 JP claimed
US-6284842-B1 WITH A POLY(SULFONYL AZIDE) THE DOW CHEMICAL COMPANY 2001-09-04 US claimed
US-6277916-B1 BY ADMIXING THE ELASTOMERIC PHASE WITH THE CURING AGENT BEFORE ADDING THE POLYOLEFIN GIVES THERMOPLASTIC PROPERTIES USEFUL IN MELTING SHAPING SUCH AS COMPRESSION MOLDING, THERMOFORMING, INJECTION MOLDING AND BLOW MOLDING THE DOW CHEMICAL COMPANY 2001-08-21 US claimed
US-6211302-B1 HEATING, COUPLING THE DOW CHEMICAL COMPANY 2001-04-03 US claimed
WO-2000078861-A1 COMPOSITION AND FILMS THEREOF THE DOW CHEMICAL COMPANY (US) 2000-12-28 WO claimed
WO-2000052091-A1 PROCESS FOR PREPARING THERMOPLASTIC VULCANIZATES THE DOW CHEMICAL COMPANY (US) 2000-09-08 WO claimed
EP-1007590-A1 RHEOLOGY MODIFICATION OF POLYMERS PREPARED USING METALLOCENES THE DOW CHEMICAL COMPANY (US) 2000-06-14 EP claimed
US-6054540-A MELT PROCESSABILITY; COUPLING USING POLYSULFONYLAZIDE THE DOW CHEMICAL COMPANY (US) 2000-04-25 US claimed
WO-1999010427-A1 RHEOLOGY MODIFICATION OF POLYMERS PREPARED USING METALLOCENES THE DOW CHEMICAL COMPANY (US) 1999-03-04 WO claimed