SCHEMBL43299

SCHEMBL43299

NCCCc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.64

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.64
TSHR P16473 1/20 0.60
KCNJ1 P48048 2/20 0.56
IDO1 P14902 3/20 0.53
KCNH2 Q12809 2/20 0.53
HRH3 Q9Y5N1 1/20 0.50
SIGMAR1 Q99720 1/20 0.50
ALDH1A1 P00352 2/20 0.48
CHRM2 P08172 1/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7504059 0.98 LOXL2 (0.62) LOXL2TSHRKCNJ1IDO1KCNH2
SCHEMBL1334549 0.94 LOXL2 (0.62) LOXL2TSHRKCNJ1IDO1KCNH2
Bromide SCHEMBL10353479 0.92 LOXL2 (0.60) LOXL2TSHRKCNJ1IDO1KCNH2
SCHEMBL15807619 0.92 LOXL2 (0.60) LOXL2TSHRKCNJ1IDO1KCNH2
Hydrochloric Acid SCHEMBL17260639 0.92 LOXL2 (0.60) LOXL2TSHRKCNJ1IDO1KCNH2
SCHEMBL335044 0.88 LOXL2 (0.69) LOXL2TSHRKCNJ1IDO1KCNH2
SCHEMBL18913824 0.87 TSHR (0.69) LOXL2TSHRKCNJ1IDO1KCNH2
SCHEMBL30758863 0.87 TSHR (0.69) LOXL2TSHRKCNJ1IDO1KCNH2
SCHEMBL22408761 0.87 KCNJ1 (0.55) LOXL2TSHRKCNJ1IDO1KCNH2
SCHEMBL16572121 0.86 KCNH2 (0.57) LOXL2TSHRKCNJ1IDO1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121431735-B Characterization method of molecular weight and molecular weight distribution of crystalline polyaryletherketone 吉林大学 2026-05-19 CN claimed
EP-3041365-B1 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RU-MINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS BV (NL) 2018-04-04 EP claimed
EP-3041365-A1 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RU-MINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP Assets B.V. (NL) 2016-07-13 EP claimed
US-20160183564-A1 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RUMINANTS, AND OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2016-06-30 US claimed
EP-2830434-B1 USE OF PARA NITRO AMINO DERIVATIVES IN FEED FOR REDUCING ME-THANE EMISSION IN RUMINANTS DSM IP ASSETS BV (NL) 2016-03-16 EP claimed
US-20150064305-A1 USE OF PARA NITRO AMINO DERIVATIVES IN FEED FOR REDUCING METH-ANE EMISSION IN RUMINANTS DSM IP ASSETS B.V. (NL) 2015-03-05 US claimed
WO-2015018726-A1 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RU-MINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2015-02-12 WO claimed
EP-2830434-A1 USE OF PARA NITRO AMINO DERIVATIVES IN FEED FOR REDUCING ME-THANE EMISSION IN RUMINANTS DSM IP Assets B.V. (NL) 2015-02-04 EP claimed
WO-2013144786-A1 USE OF PARA NITRO AMINO DERIVATIVES IN FEED FOR REDUCING ME-THANE EMISSION IN RUMINANTS DSM IP ASSETS B.V. (NL) 2013-10-03 WO claimed
EP-2644038-A1 Use of para nitro amino derivatives in feed for reducing meth-ane emission in ruminants DSM IP Assets B.V. (NL) 2013-10-02 EP claimed
CN-121431735-B Characterization method of molecular weight and molecular weight distribution of crystalline polyaryletherketone 吉林大学 2026-05-19 CN disclosed
CN-118290816-A Recovery method of fiber-reinforced polyaryletherketone resin matrix composite material 吉林大学 2024-07-05 CN disclosed
US-20230027075-A1 SULFONAMIDE COMPOUNDS TARGETING CD73 AND ADENOSINE RECEPTORS AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) 2023-01-26 US disclosed
EP-4065590-A1 SULFONAMIDE COMPOUNDS TARGETING CD73 AND ADENOSINE RECEPTORS Aurigene Discovery Technologies Limited (IN) 2022-10-05 EP disclosed
CN-114728998-A Sulfonamide compounds targeting CD73 and adenosine receptors 奥瑞基尼探索技术有限公司 2022-07-08 CN disclosed
WO-1992002214-A1 AICA RIBOSIDE ANALOGS GENSIA PHARMACEUTICALS, INC. (US) 1992-02-20 WO disclosed
WO-1992002213-A1 METHODS OF PREVENTING OR DECREASING TISSUE DAMAGE BY NOVEL ANTIOXIDANTS AND FREE RADICAL SCAVENGERS GENSIA PHARMACEUTICALS, INC. (US) 1992-02-20 WO disclosed
US-5008267-A Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1991-04-16 US disclosed
EP-0404146-A2 Enantiomeric enrichment and stereoselective synthesis of chiral amines CELGENE CORPORATION (US) 1990-12-27 EP disclosed
EP-0369627-A2 Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230027075-A1 SULFONAMIDE COMPOUNDS TARGETING CD73 AND ADENOSINE RECEPTORS ADORA2A, ADORA2B, ENTPD5 LOXL2 3751/4885TSHR 134/4885KCNJ1 1515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.