Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.78 |
| ▸ | NPC1 | O15118 | 7/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.78 |
| ▸ | MEN1 | O00255 | 5/20 | 0.78 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.74 |
| ▸ | CASP3 | P42574 | 1/20 | 0.73 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | PLAU | P00749 | 3/20 | 0.61 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26885264 | 0.95 | RAB9A (0.72) | RAB9ANPC1KMT2AMEN1DEGS1 | |
| SCHEMBL2230642 | 0.90 | NPC1 (0.77) | RAB9ANPC1KMT2AMEN1DEGS1 | |
| SCHEMBL12447826 | 0.87 | NPC1 (0.82) | RAB9ANPC1KMT2AMEN1DEGS1 | |
| SCHEMBL26885220 | 0.87 | DEGS1 (0.79) | RAB9ANPC1KMT2AMEN1DEGS1 | |
| SCHEMBL2467402 | 0.86 | PLAU (0.78) | RAB9ANPC1KMT2AMEN1DEGS1 | |
| SCHEMBL15711275 | 0.86 | NPC1 (0.70) | RAB9ANPC1KMT2AMEN1DEGS1 | |
| SCHEMBL3656661 | 0.85 | DEGS1 (0.77) | RAB9ANPC1KMT2AMEN1DEGS1 | |
| SCHEMBL7890716 | 0.85 | DEGS1 (1.00) | RAB9ANPC1KMT2AMEN1DEGS1 | |
| SCHEMBL29518660 | 0.85 | DEGS1 (1.00) | RAB9ANPC1KMT2AMEN1DEGS1 | |
| SCHEMBL3788361 | 0.84 | NPC1 (1.00) | RAB9ANPC1KMT2AMEN1DEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |