Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 1.00 |
| ▸ | MME | P08473 | 3/20 | 1.00 |
| ▸ | APP | P05067 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Omapatrilat SCHEMBL30924348 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| Omapatrilat SCHEMBL1047530 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| Omapatrilat SCHEMBL130098 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| Omapatrilat SCHEMBL30924347 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| Omapatrilat SCHEMBL4818275 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| Omapatrilat SCHEMBL23468397 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| Omapatrilat SCHEMBL20130837 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| Omapatrilat SCHEMBL49355 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| SCHEMBL6891502 | 0.94 | ACE (0.89) | ACEMMEAPP | |
| SCHEMBL6894003 | 0.94 | ACE (0.89) | ACEMMEAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061518-A2 | RADIOIMAGING MOIETIES COUPLED TO PEPTIDASE-BINDING MOIETIES FOR IMAGING TISSUES AND ORGANS THAT EXPRESS PEPTIDASES | Molecular Insight Pharmaceuticals, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| US-20080213172-A1 | RADIOIMAGING MOIETIES COUPLED TO PEPTIDEASE-BINDING MOIETIES FOR IMAGING TISSUES AND ORGANS THAT EXPRESS PEPTIDASES | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2008-09-04 | — | — | US | disclosed |
| WO-2008028000-A2 | RADIOIMAGING MOIETIES COUPLED TO PEPTIDASE-BINDING MOIETIES FOR IMAGING TISSUES AND ORGANS THAT EXPRESS PEPTIDASES | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2008-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080213172-A1 | RADIOIMAGING MOIETIES COUPLED TO PEPTIDEASE-BINDING MOIETIES FOR IMAGING TISSUES AND ORGANS THAT EXPRESS PEPTIDASES | LAP3, DNPEP, ACE | ACE 3/4885MME 5/4885APP 1078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.