Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 1.00 |
| ▸ | MME | P08473 | 3/20 | 1.00 |
| ▸ | APP | P05067 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Omapatrilat SCHEMBL30924348 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| Omapatrilat SCHEMBL4330098 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| Omapatrilat SCHEMBL1047530 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| Omapatrilat SCHEMBL30924347 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| Omapatrilat SCHEMBL4818275 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| Omapatrilat SCHEMBL23468397 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| Omapatrilat SCHEMBL20130837 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| Omapatrilat SCHEMBL49355 | 1.00 | ACE (1.00) | ACEMMEAPP | |
| SCHEMBL6891502 | 0.94 | ACE (0.89) | ACEMMEAPP | |
| SCHEMBL6894003 | 0.94 | ACE (0.89) | ACEMMEAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 871 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250340573-A1 | THE SYNTHESIS OF OMAPATRILAT | ENDOTHELIUM SCANNING NANOTECHNOLOGY LTD (AU) | 2025-11-06 | — | — | US | claimed |
| EP-4619408-A1 | THE SYNTHESIS OF OMAPATRILAT | Endothelium Scanning Nanotechnology Limited (AU) | 2025-09-24 | — | — | EP | claimed |
| WO-2024103123-A1 | THE SYNTHESIS OF OMAPATRILAT | Endothelium Scanning Nanotechnology Limited (AU) | 2024-05-23 | — | — | WO | claimed |
| US-20220112240-A1 | BRANCHED PEPTIDES FOR ENZYMATIC ASSEMBLY AND MITOCHONDRIA DRUG DELIVERY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-04-14 | — | — | US | claimed |
| EP-1778234-B2 | PIMOBENDAN TO BE USED FOR THE REDUCTION OF HEART SIZE IN MAMMALS SUFFERING FROM HEART FAILURE | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2021-06-23 | — | — | EP | claimed |
| US-20200179440-A1 | THIOL AND DISULFIDE-CONTAINING AGENTS FOR INCREASING MEIBOMIAN GLAND LIPID SECRETION | M.G. THERAPEUTICS LTD. (IL) | 2020-06-11 | — | — | US | claimed |
| EP-2661431-B1 | HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK | BIOENERGENIX (US) | 2018-07-11 | — | — | EP | claimed |
| EP-3313413-A2 | THIOL AND DISULFIDE-CONTAINING AGENTS FOR INCREASING MEIBOMIAN GLAND LIPID SECRETION | AZURA OPTHALMICS LTD. (IL) | 2018-05-02 | — | — | EP | claimed |
| EP-2150526-B1 | N-ADAMANTYL BENZAMIDES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE | VTV THERAPEUTICS LLC (US) | 2017-09-20 | — | — | EP | claimed |
| US-20170087179-A1 | Thiol and Disulfide-Containing Agents for Increasing Meibomian Gland Lipid Secretion | Azura Ophthalmics Ltd. (IL) | 2017-03-30 | — | — | US | claimed |
| US-20030125575-A1 | Process for the preparation of(R)-2-bromo-3-phenyl -propionic acid | DSM N.V. (NL) | 2003-07-03 | — | — | US | claimed |
| US-20030120102-A1 | Method for the preparation of (s) -2-acetylthio-3-phenylpropionic acid | DSM IP ASSETS B.V. (NL) | 2003-06-26 | — | — | US | claimed |
| CN-1425001-A | Process for preparing -2-acetylthio-3-phenylpropionic acid | DSM NV (NL) | 2003-06-18 | — | — | CN | claimed |
| WO-2003043615-A2 | HYPERTONIA TREATMENT DURING THE ACUTE PHASE OF A CEREBROVASCULAR ACCIDENT | SOLVAY PHARMACEUTICALS GMBH (DE) | 2003-05-30 | — | — | WO | claimed |
| CN-1416414-A | Process for preparing -2-bromo-3-phenylpropionic acid | DSM NV (NL) | 2003-05-07 | — | — | CN | claimed |
| EP-1272452-A2 | PROCESS FOR THE PREPARATION OF (R)-2-BROMO-3-PHENYL-PROPIONIC ACID | DSM N.V. (NL) | 2003-01-08 | — | — | EP | claimed |
| EP-1272466-A1 | METHOD FOR THE PREPARATION OF (S)-2-ACETYLTHIO-3-PHENYLPROPIONIC ACID | DSM N.V. (NL) | 2003-01-08 | — | — | EP | claimed |
| WO-2002017958-A1 | AGENT FOR INFLUENCING ANGIOGENESIS | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2002-03-07 | — | — | WO | claimed |
| WO-2001058837-A2 | PROCESS FOR THE PREPARATION OF (R)-2-BROMO-3-PHENYL-PROPIONIC ACID | DSM N.V. (NL) | 2001-08-16 | — | — | WO | claimed |
| WO-2001058865-A1 | METHOD FOR THE PREPARATION OF (S)-2-ACETYLTHIO-3-PHENYLPROPIONIC ACID | DSM N.V. (NL) | 2001-08-16 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170087179-A1 | Thiol and Disulfide-Containing Agents for Increasing Meibomian Gland Lipid Secretion | TXN, MGST3, MGST1 | ACE 3798/4885MME 968/4885APP 3576/4885 |
| US-20250340573-A1 | THE SYNTHESIS OF OMAPATRILAT | PARP1, PDE7A, TBXAS1 | ACE 96/4885MME 1469/4885APP 3155/4885 |
| US-20200179440-A1 | THIOL AND DISULFIDE-CONTAINING AGENTS FOR INCREASING MEIBOMIAN GLAND LIPID SECRETION | TXN, MGST3, MGST1 | ACE 3798/4885MME 968/4885APP 3576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.