Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | MTAP | Q13126 | 4/20 | 0.32 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330244 | 1.00 | MEN1 (0.37) | MEN1KMT2AASAH1TGFBR1MTAP | |
| SCHEMBL25207337 | 0.81 | PDE4A (0.39) | MEN1KMT2AASAH1TGFBR1DEGS1 | |
| SCHEMBL16215024 | 0.75 | CA1 (0.49) | KMT2A | |
| SCHEMBL9007649 | 0.75 | MEN1 (0.35) | MEN1KMT2AASAH1DEGS1OR51E2 | |
| SCHEMBL9007655 | 0.75 | MEN1 (0.35) | MEN1KMT2AASAH1DEGS1OR51E2 | |
| SCHEMBL16468486 | 0.74 | PAX8 (0.38) | MEN1KMT2AASAH1TGFBR1PAX8 | |
| SCHEMBL3743604 | 0.74 | PAX8 (0.38) | MEN1KMT2AASAH1TGFBR1PAX8 | |
| SCHEMBL20572594 | 0.74 | PAX8 (0.38) | MEN1KMT2AASAH1TGFBR1PAX8 | |
| SCHEMBL25173479 | 0.74 | PAX8 (0.38) | MEN1KMT2AASAH1TGFBR1PAX8 | |
| SCHEMBL3743599 | 0.74 | PAX8 (0.38) | MEN1KMT2AASAH1TGFBR1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049543-B1 | ACYCLIC AMINE INHIBITORS OF 5'-METHYLTHIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE | CALLAGHAN INNOVATION RES LTD (NZ) | 2014-11-05 | — | — | EP | disclosed |
| US-8383636-B2 | Acyclic amine inhibitors of 5-methytioadenosine phosphorylase and nucleosidase | INDUSTRIAL RESEARCH LIMITED (NZ) | 2013-02-26 | — | — | US | disclosed |
| EP-2049543-A1 | ACYCLIC AMINE INHIBITORS OF 5'-METHYLTHIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008030118-A1 | ACYCLIC AMINE INHIBITORS OF 5'-METHYLTHIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE | INDUSTRIAL RESEARCH LIMITED (NZ) | 2008-03-13 | — | — | WO | disclosed |