SCHEMBL25207337

SCHEMBL25207337

O=C(O)NC(CO)C(O)CO

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ASAH1 Q13510 1/20 0.37
LMNA P02545 2/20 0.37
USP2 O75604 1/20 0.37
SLCO1B1 Q9Y6L6 1/20 0.37
OR51E2 Q9H255 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
DEGS1 O15121 1/20 0.33
PAX8 Q06710 1/20 0.32
TGFBR1 P36897 1/20 0.31
KDM4E B2RXH2 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9007649 0.84 MEN1 (0.35) PDE4AMEN1KMT2AASAH1OR51E2
SCHEMBL9007655 0.84 MEN1 (0.35) PDE4AMEN1KMT2AASAH1OR51E2
SCHEMBL18981606 0.84 PDE4A (0.50) PDE4AMEN1KMT2AASAH1LMNA
SCHEMBL4330104 0.81 MEN1 (0.37) MEN1KMT2AASAH1OR51E2DEGS1
SCHEMBL4330244 0.81 MEN1 (0.37) MEN1KMT2AASAH1OR51E2DEGS1
SCHEMBL3743604 0.78 PAX8 (0.38) MEN1KMT2AASAH1LMNAOR51E2
SCHEMBL16468486 0.78 PAX8 (0.38) MEN1KMT2AASAH1LMNAOR51E2
SCHEMBL20572594 0.78 PAX8 (0.38) MEN1KMT2AASAH1LMNAOR51E2
SCHEMBL5936379 0.78 MAPT (0.45) PDE4AMEN1KMT2AASAH1LMNA
SCHEMBL5936381 0.78 MAPT (0.45) PDE4AMEN1KMT2AASAH1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R PDE4A 2361/4885MEN1 1529/4885KMT2A 2580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.