SCHEMBL4330127

SCHEMBL4330127

CCCCC(OC(=O)c1ccc(N)cc1)OC(=O)c1ccc(N)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.59
CYP3A4 P08684 4/20 0.59
CYP1A2 P05177 4/20 0.59
TSHR P16473 4/20 0.59
CYP2C19 P33261 2/20 0.59
CYP2C9 P11712 1/20 0.59
PDE4D Q08499 1/20 0.59
ALDH1A1 P00352 2/20 0.56
NPC1 O15118 1/20 0.56
MAPT P10636 1/20 0.56
RAB9A P51151 1/20 0.56
MAOA P21397 2/20 0.53
CYP2D6 P10635 3/20 0.51
SCN1A P35498 2/20 0.51
SCN2A Q99250 2/20 0.51
SCN3A Q9NY46 2/20 0.51
SLC6A3 Q01959 2/20 0.51
CHRM2 P08172 1/20 0.51
HTR1A P08908 1/20 0.51
GAA P10253 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4330726 0.95 MAPT (0.59) LMNACYP3A4CYP1A2TSHRCYP2C19
SCHEMBL4331337 0.94 MAPT (0.61) LMNACYP3A4CYP1A2TSHRCYP2C19
SCHEMBL4558857 0.94 MAPT (0.61) LMNACYP3A4CYP1A2TSHRCYP2C19
SCHEMBL4345498 0.94 MAPT (0.61) LMNACYP3A4CYP1A2TSHRCYP2C19
SCHEMBL4557167 0.94 MAPT (0.61) LMNACYP3A4CYP1A2TSHRCYP2C19
SCHEMBL4329440 0.94 MAPT (0.61) LMNACYP3A4CYP1A2TSHRCYP2C19
SCHEMBL4340299 0.94 MAPT (0.61) LMNACYP3A4CYP1A2TSHRCYP2C19
SCHEMBL4334900 0.94 MAPT (0.61) LMNACYP3A4CYP1A2TSHRCYP2C19
SCHEMBL1257360 0.90 LMNA (0.56) LMNACYP3A4CYP1A2TSHRCYP2C19
SCHEMBL9068778 0.86 LMNA (0.58) LMNACYP3A4CYP1A2TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615260-B2 Active-matrix liquid crystal display HITACHI, LTD. (JP) 2009-11-10 US disclosed
US-20050012884-A1 Active-matrix liquid crystal display IPS ALPHA SUPPORT CO., LTD. (JP) 2005-01-20 US disclosed
EP-0806698-B1 In-plane switching-mode active-matrix liquid crystal display HITACHI LTD (JP) 2005-01-12 EP disclosed
US-6756089-B2 MULTILAYER; POLYAMIDEIMIDE COPOLYMER HITACHI, LTD. (JP) 2004-06-29 US disclosed
US-20010046569-A1 Active-matrix liquid crystal display IPS ALPHA SUPPORT CO., LTD. (JP) 2001-11-29 US disclosed
US-6242060-B1 MULTILAYER HITACHI, LTD. (JP) 2001-06-05 US disclosed
US-5928733-A Active-matrix liquid crystal display HITACHI, LTD. (JP) 1999-07-27 US disclosed
EP-0806698-A1 Active-matrix liquid crystal display HITACHI, LTD. (JP) 1997-11-12 EP disclosed