SCHEMBL4334900

SCHEMBL4334900

CCCCCCCCCCCCCC(OC(=O)c1ccc(N)cc1)OC(=O)c1ccc(N)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.61
ALDH1A1 P00352 2/20 0.61
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
LMNA P02545 3/20 0.56
CYP1A2 P05177 3/20 0.56
CYP3A4 P08684 3/20 0.56
TSHR P16473 2/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
PDE4D Q08499 1/20 0.56
MAOA P21397 2/20 0.50
CYP2D6 P10635 2/20 0.49
CHRM2 P08172 1/20 0.49
HTR1A P08908 1/20 0.49
GAA P10253 1/20 0.49
DRD3 P35462 1/20 0.49
SCN1A P35498 1/20 0.49
SLC6A3 Q01959 1/20 0.49
KCNH2 Q12809 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4340299 1.00 MAPT (0.61) MAPTALDH1A1NPC1RAB9ALMNA
SCHEMBL4345498 1.00 MAPT (0.61) MAPTALDH1A1NPC1RAB9ALMNA
SCHEMBL4558857 1.00 MAPT (0.61) MAPTALDH1A1NPC1RAB9ALMNA
SCHEMBL4557167 1.00 MAPT (0.61) MAPTALDH1A1NPC1RAB9ALMNA
SCHEMBL4331337 1.00 MAPT (0.61) MAPTALDH1A1NPC1RAB9ALMNA
SCHEMBL4329440 1.00 MAPT (0.61) MAPTALDH1A1NPC1RAB9ALMNA
SCHEMBL4330726 0.98 MAPT (0.59) MAPTALDH1A1NPC1RAB9ALMNA
SCHEMBL4330127 0.94 LMNA (0.59) MAPTALDH1A1NPC1RAB9ALMNA
SCHEMBL1257360 0.87 LMNA (0.56) MAPTALDH1A1NPC1RAB9ALMNA
SCHEMBL9404038 0.87 MAPT (0.60) MAPTALDH1A1NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615260-B2 Active-matrix liquid crystal display HITACHI, LTD. (JP) 2009-11-10 US disclosed
US-20050012884-A1 Active-matrix liquid crystal display IPS ALPHA SUPPORT CO., LTD. (JP) 2005-01-20 US disclosed
EP-0806698-B1 In-plane switching-mode active-matrix liquid crystal display HITACHI LTD (JP) 2005-01-12 EP disclosed
US-6756089-B2 MULTILAYER; POLYAMIDEIMIDE COPOLYMER HITACHI, LTD. (JP) 2004-06-29 US disclosed
US-20010046569-A1 Active-matrix liquid crystal display IPS ALPHA SUPPORT CO., LTD. (JP) 2001-11-29 US disclosed
US-6242060-B1 MULTILAYER HITACHI, LTD. (JP) 2001-06-05 US disclosed
US-5928733-A Active-matrix liquid crystal display HITACHI, LTD. (JP) 1999-07-27 US disclosed
EP-0806698-A1 Active-matrix liquid crystal display HITACHI, LTD. (JP) 1997-11-12 EP disclosed