Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28582199 | 0.83 | TSHR (0.33) | TSHR | |
| SCHEMBL27881824 | 0.80 | — | — | |
| SCHEMBL5392636 | 0.78 | ALDH1A1 (0.35) | TSHRSMN1; SMN2 | |
| SCHEMBL21960166 | 0.77 | CYP2D6 (0.33) | CYP2D6 | |
| SCHEMBL27881672 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL7777535 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL10375569 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL7543248 | 0.71 | — | — | |
| SCHEMBL27258356 | 0.68 | — | — | |
| SCHEMBL12583427 | 0.67 | TSHR (0.38) | CYP2D6TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032142-A2 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-03-11 | — | — | EP | claimed |
| WO-2007147109-A2 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-12-21 | — | — | WO | claimed |
| EP-1379724-A1 | HYDROPHILICALLY MODIFIED POLYISOCYANATES AND POLYURETHANES FOR CREASE-PROOFING TEXTILES CONTAINING CELLULOSE | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002038852-A1 | HYDROPHILICALLY MODIFIED POLYISOCYANATES AND POLYURETHANES FOR CREASE-PROOFING TEXTILES CONTAINING CELLULOSE | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-16 | — | — | WO | disclosed |
| EP-0191662-B1 | PRISTINAMYCINE IIB DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1988-06-01 | — | — | EP | disclosed |
| EP-0191662-A1 | Pristinamycine IIB derivatives, their preparation and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1986-08-20 | — | — | EP | disclosed |