Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330782 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL4336889 | 0.90 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL4336892 | 0.90 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL4334401 | 0.89 | MAPT (0.48) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL13612377 | 0.89 | MAPT (0.48) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL4334398 | 0.82 | POLB (0.48) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL4334393 | 0.82 | NPC1 (0.50) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL4336786 | 0.80 | SMN1; SMN2 (0.62) | ALDH1A1MAPTKMT2ACTSLNPC1 | |
| SCHEMBL4336780 | 0.80 | SMN1; SMN2 (0.62) | ALDH1A1MAPTKMT2ACTSLNPC1 | |
| SCHEMBL13612327 | 0.80 | MAPT (0.50) | ALDH1A1MAPTKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090285849-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285849-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | MAVS, IRF3, HAVCR2 | ALDH1A1 1459/4885MAPT 3619/4885KMT2A 3988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.