SCHEMBL4331002

SCHEMBL4331002

C=CC(=O)O[C](C)OC(=O)C=C

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.47
TSHR P16473 11/20 0.41
HPGD P15428 1/20 0.39
TP53 P04637 4/20 0.39
HIF1A Q16665 3/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP3A4 P08684 2/20 0.39
LMNA P02545 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
FGFR4 P22455 1/20 0.33
THRB P10828 2/20 0.32
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27795137 0.87
SCHEMBL475313 0.82
Acetic Acid SCHEMBL27649268 0.82 ALDH1A1 (0.47) ALDH1A1TSHRHPGDTP53HIF1A
SCHEMBL6350283 0.82
SCHEMBL27273791 0.81 TSHR (0.45) ALDH1A1TSHRHPGDTP53HIF1A
SCHEMBL278164 0.81
SCHEMBL1148750 0.80
SCHEMBL21954820 0.80
SCHEMBL864808 0.80
SCHEMBL3273152 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1489158-B1 Friction modifier composition SANYO CHEMICAL IND LTD (JP) 2012-06-20 EP disclosed
US-7579305-B2 Friction regulator for lubricating oil and lubricating oil composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2009-08-25 US disclosed
US-20070287644-A1 LUBRICATING OIL COMPOSITION SHELL OIL COMPANY 2007-12-13 US disclosed
EP-1860175-A2 Lubricating oil composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2007-11-28 EP disclosed
US-20060105924-A1 Friction regulator for lubricating oil and lubricating oil composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-05-18 US disclosed
EP-1489158-A1 FRICTION REGULATOR FOR LUBRICATING OIL AND LUBRICATING OIL COMPOSITION SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2004-12-22 EP disclosed
EP-0264827-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1993-01-07 EP disclosed
US-4833116-A MULTILAYER, COLOR IMAGES KANZAKI PAPER MFG. CO., LTD. (JP) 1989-05-23 US disclosed
EP-0264827-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1988-04-27 EP disclosed
US-4517050-A ETCHING AND DEFORMING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-05-14 US disclosed
US-4501638-A Liquid chemical process for forming conductive through-holes through a dielectric layer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-02-26 US disclosed
US-4351881-A WEAR RESISTANCE, DYEABILITY MITSUBISHI RAYON CO., LTD. (JP) 1982-09-28 US disclosed
US-4291097-A PHOTOPOLYMERIZATION OF AN ACRYLIC ESTER MIXTURE WITH PHOSPHORIC ACID ESTER AND AN ETHANOLAMINE MITSUBISHI RAYON CO., LTD. (JP) 1981-09-22 US disclosed
US-4274933-A FORMING A CROSSLINKED HARDENED FILM ON A SUBSTRATE MITSUBISHI RAYON CO., LTD. (JP) 1981-06-23 US disclosed