⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595889 | 0.97 | — | — | |
| Bicarbonate SCHEMBL18149158 | 0.95 | HSD17B10 (0.48) | — | |
| Chloromethane SCHEMBL28424742 | 0.95 | HSD17B10 (0.48) | — | |
| Urea SCHEMBL27938736 | 0.93 | TDP1 (0.46) | — | |
| SCHEMBL27826345 | 0.89 | HSD17B10 (0.42) | — | |
| SCHEMBL22418805 | 0.81 | ALDH1A1 (0.43) | — | |
| SCHEMBL6350283 | 0.80 | — | — | |
| SCHEMBL4331002 | 0.80 | ALDH1A1 (0.47) | — | |
| SCHEMBL5455988 | 0.80 | TDP1 (0.55) | — | |
| SCHEMBL5456001 | 0.80 | TDP1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585437-A | Eribulin Process for the preparation of intermediates | 上海皓元医药股份有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-115323011-A | Preparation method of eribulin intermediate | 上海皓元医药股份有限公司 | 2022-11-11 | — | — | CN | claimed |
| CN-109824350-A | A kind of preparation method of ceramics resistant brick | 高阳 | 2019-05-31 | — | — | CN | claimed |
| US-10280247-B2 | Non-aqueous cross-linkable fluoropolymer compositions | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2019-05-07 | — | — | US | claimed |
| US-20180079850-A1 | NON-AQUEOUS CROSS-LINKABLE FLUOROPOLYMER COMPOSITIONS | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2018-03-22 | — | — | US | claimed |
| EP-3274389-A1 | NON-AQUEOUS CROSS-LINKABLE FLUOROPOLYMER COMPOSITIONS | Solvay Specialty Polymers Italy S.p.A. (IT) | 2018-01-31 | — | — | EP | claimed |
| CN-107428903-A | Non-aqueous crosslinkable fluoropolymer compositions | 索尔维特殊聚合物意大利有限公司 | 2017-12-01 | — | — | CN | claimed |
| EP-2739662-B1 | COMPOSITIONS OF IONISABLE FLUOROPOLYMERS | SOLVAY SPECIALTY POLYMERS IT (IT) | 2017-05-17 | — | — | EP | claimed |
| WO-2016150942-A1 | NON-AQUEOUS CROSS-LINKABLE FLUOROPOLYMER COMPOSITIONS | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2016-09-29 | — | — | WO | claimed |
| US-9090772-B2 | Compositions of ionisable fluoropolymers | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2015-07-28 | — | — | US | claimed |
| WO-2013017470-A9 | COMPOSITIONS OF IONISABLE FLUOROPOLYMERS | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2013-04-11 | — | — | WO | claimed |
| WO-2013017470-A1 | COMPOSITIONS OF IONISABLE FLUOROPOLYMERS | SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) | 2013-02-07 | — | — | WO | claimed |
| CN-101407489-B | 2-alkyl acrylate compounds and uses thereof | SINOCHEM CORP | 2011-06-01 | — | — | CN | claimed |
| CN-101407489-A | 2-alkyl acrylate compounds and uses thereof | SINOCHEM CORP (CN) | 2009-04-15 | — | — | CN | claimed |
| CN-1202075-C | One-pot synthesis of alkyl 3-cyclopropylamino-2-[2,4-dibromo-3-(difruoro methoxy)benzoyl]-2-propenoate as useful intermediate for antibacterial quinolone medicaments | RANBAXY LAB LTD (IN) | 2005-05-18 | — | — | CN | claimed |
| CN-1427815-A | One-pot synthesis of alkyl 3-cyclopropylamino-2- [2, 4-dibromo-3- (difluoromethoxy) benzoyl ] -2-propenoate as a useful intermediate for antibacterial quinolone drugs | RANBAXY LAB LTD (IN) | 2003-07-02 | — | — | CN | claimed |
| US-5412038-A | Process utilizing alkenylcarboxylate crosslinkers | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-05-02 | — | — | US | claimed |
| EP-0469055-A1 | SOAP BARS WITH POLYMERIC ADDITIVES. | UNILEVER PLC (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990012863-A1 | SOAP BARS WITH POLYMERIC ADDITIVES | UNILEVER PLC (GB) | 1990-11-01 | — | — | WO | claimed |
| EP-0086051-B1 | PRODUCTION OF PHOTOCURABLE COMPOSITIONS | MORTON THIOKOL, INC. (US) | 1986-12-30 | — | — | EP | claimed |