SCHEMBL4331139

SCHEMBL4331139

CC(C)(C)c1cc(CC[C]=O)cc(C(C)(C)C(=O)NN)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.57
KMT2A Q03164 5/20 0.44
MEN1 O00255 4/20 0.41
ALDH1A1 P00352 5/20 0.38
TSHR P16473 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
MAPK1 P28482 2/20 0.38
BLM P54132 2/20 0.38
ATM Q13315 2/20 0.38
HIF1A Q16665 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
USP2 O75604 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38
LMNA P02545 3/20 0.38
GSR P00390 2/20 0.38
TDP1 Q9NUW8 1/20 0.37
GMNN O75496 1/20 0.37
GABBR2 O75899 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265388 0.84 GAA (0.53) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL9447227 0.82 GAA (0.57) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL9408809 0.76 CYP1A2 (0.49) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL1185721 0.74 GAA (0.69) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL3455767 0.73 GAA (1.00) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL315837 0.73 GAA (1.00) GAAKMT2AMEN1ALDH1A1TSHR
Acetone SCHEMBL28508906 0.71 GAA (0.94) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL8340038 0.70 GAA (0.73) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL9575147 0.70 GAA (0.62) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL284696 0.69 ALDH1A1 (0.63) GAAKMT2AMEN1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8303851-B2 Stabilizers, organic or inorganic pigments, and/orone or more dyes, obtained by extrusion at lowest melting temperature GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2012-11-06 US disclosed
EP-1565522-B1 USE OF POLYMER POWDER CONTAINING UV ABSORBER FOR THE STABILISATION OF POLYMERS AGAINST THE EFFECTS OF UV RADIATION BASF SE (DE) 2009-10-14 EP disclosed
US-20080194766-A1 Mixtures of Additives For Organic Polymers In Granular Form GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2008-08-14 US disclosed
EP-1788015-A1 Use of polymer powder containing UV absorber for the stabilisation of polymers against the efects of UV radiation BASF Aktiengesellschaft (DE) 2007-05-23 EP disclosed
EP-1276802-A1 LIQUID STABILIZING MIXTURES FOR ORGANIC POLYMERS Great Lakes Chemical (Europe) GmbH (CH) 2003-01-22 EP disclosed
EP-1268633-A1 STABILIZING MIXTURES FOR ORGANIC POLYMERS Great Lakes Chemical (Europe) GmbH (CH) 2003-01-02 EP disclosed
WO-2001081458-A1 LIQUID STABILIZING MIXTURES FOR ORGANIC POLYMERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2001-11-01 WO disclosed
WO-2001070868-A1 STABLILIZING MIXTURES FOR ORGANIC POLYMERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2001-09-27 WO disclosed