Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.43 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455516 | 0.87 | STS (0.46) | SLC6A4SLC6A2SLC6A3HRH3ALDH1A1 | |
| SCHEMBL4316512 | 0.84 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4328719 | 0.83 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4459508 | 0.82 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4338598 | 0.82 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4316588 | 0.76 | KMT2A (0.43) | SLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL4321880 | 0.74 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4316957 | 0.74 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3HRH3ALDH1A1 | |
| SCHEMBL4451508 | 0.73 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4326421 | 0.72 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | claimed |