Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331669 | 0.87 | SLC6A4 (0.49) | ALDH1A1SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4326153 | 0.85 | MAPK1 (0.43) | STSGPR119 | |
| SCHEMBL4316512 | 0.80 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4328719 | 0.79 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4459508 | 0.78 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4338598 | 0.78 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4316588 | 0.72 | KMT2A (0.43) | ALDH1A1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL22792662 | 0.72 | STS (0.47) | STSALDH1A1GPR119EPHX2PIK3CA | |
| SCHEMBL327514 | 0.71 | STS (0.48) | STSALDH1A1GPR119HRH3EPHX2 | |
| SCHEMBL4316957 | 0.70 | SLC6A4 (0.39) | ALDH1A1SLC6A4SLC6A2SLC6A3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |