SCHEMBL6632283

SCHEMBL6632283

[CH2]CC(CCCC(=O)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 11/20 0.57
LMNA P02545 2/20 0.43
SLC22A6 Q4U2R8 1/20 0.43
ENPEP Q07075 2/20 0.42
GSTK1 Q9Y2Q3 2/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
PMP22 Q01453 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4331999 0.86 FOLH1 (0.62) FOLH1
SCHEMBL11777462 0.84 FOLH1 (0.55) FOLH1LMNASLC22A6ENPEPGSTK1
SCHEMBL11238060 0.83 FOLH1 (0.65) FOLH1LMNASLC22A6ENPEPGSTK1
SCHEMBL5692955 0.81 FOLH1 (0.67) FOLH1LMNASLC22A6GSTK1TSHR
SCHEMBL500865 0.81 FOLH1 (0.73) FOLH1
SCHEMBL9538314 0.81 FOLH1 (0.63) FOLH1LMNASLC22A6ENPEPGSTK1
SCHEMBL480069 0.79 CHRM1 (0.42) FOLH1
SCHEMBL2483229 0.79 FOLH1 (0.74) FOLH1LMNASLC22A6ENPEPTSHR
SCHEMBL8075329 0.78 FOLH1 (0.55) FOLH1LMNAENPEPGSTK1TSHR
SCHEMBL7863633 0.78 FOLH1 (0.55) FOLH1LMNAENPEPGSTK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10759749-B2 Therapeutic agent for diabetes JCR PHARMACEUTICALS CO., LTD. (JP) 2020-09-01 US disclosed
EP-3508474-A1 NOVEL THERAPEUTIC AGENT FOR DIABETES JCR Pharmaceuticals Co., Ltd. (JP) 2019-07-10 EP disclosed
US-20190202781-A1 NOVEL THERAPEUTIC AGENT FOR DIABETES JCR PHARMACEUTICALS CO., LTD. (JP) 2019-07-04 US disclosed
US-10256169-B2 Semiconductor device FUJI ELECTRIC CO., LTD. (JP) 2019-04-09 US disclosed
US-20170278771-A1 SEMICONDUCTOR DEVICE FUJI ELECTRIC CO., LTD. (JP) 2017-09-28 US disclosed
CN-1276035-C Water-color ink MITSUI CHEMICALS INC (JP) 2006-09-20 CN disclosed
CN-1558934-A Water-color ink 三井化学株式会社 2004-12-29 CN disclosed
US-20040231558-A1 Has a clear hue, high light fastness and high moisture resistance MITSUI CHEMICALS, INC. (JP) 2004-11-25 US disclosed
EP-1441013-A1 WATERCOLOR INK Mitsui Chemicals, Inc. (JP) 2004-07-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202781-A1 NOVEL THERAPEUTIC AGENT FOR DIABETES GPR119, IAPP, DPP4 FOLH1 1309/4885LMNA 4657/4885SLC22A6 1171/4885
US-10759749-B2 Therapeutic agent for diabetes GPR119, IAPP, DPP4 FOLH1 1428/4885LMNA 4517/4885SLC22A6 1376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.