SCHEMBL4332055

SCHEMBL4332055

CC(C)Oc1ccccc1COC(=O)OCc1ccccc1OC(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.49
IRAK4 Q9NWZ3 2/20 0.49
ALDH1A1 P00352 3/20 0.46
ACHE P22303 1/20 0.46
KDM4E B2RXH2 2/20 0.43
LMNA P02545 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
TAS1R3 Q7RTX0 1/20 0.43
TAS1R1 Q7RTX1 1/20 0.43
TSHR P16473 2/20 0.41
HPGD P15428 2/20 0.41
USP2 O75604 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TSPO P30536 1/20 0.40
IDO1 P14902 1/20 0.40
TDO2 P48775 1/20 0.40
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
KCNH2 Q12809 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25720977 0.90 FFAR4 (0.49) FFAR4IRAK4ALDH1A1ACHEKDM4E
SCHEMBL4342986 0.88 FFAR4 (0.46) FFAR4IRAK4ALDH1A1ACHEKDM4E
SCHEMBL11393662 0.87 IRAK4 (0.54) FFAR4IRAK4ALDH1A1ACHEKDM4E
SCHEMBL27339806 0.82 FFAR4 (0.44) FFAR4IRAK4ALDH1A1ACHEKDM4E
SCHEMBL286684 0.80 IDO1 (0.58) ALDH1A1HPGDSMN1; SMN2NPSR1IDO1
SCHEMBL17942368 0.80 ALDH1A1 (0.45) ALDH1A1KDM4ELMNATSHRSMN1; SMN2
SCHEMBL18504836 0.78 FFAR4 (0.44) FFAR4IRAK4ALDH1A1ACHEKDM4E
SCHEMBL22311627 0.78 IDO1 (0.46) FFAR4IRAK4ALDH1A1ACHEKDM4E
SCHEMBL1404966 0.78 ALDH1A1 (0.51) FFAR4IRAK4ALDH1A1ACHEKDM4E
SCHEMBL8023122 0.78 FFAR4 (0.61) FFAR4IRAK4ALDH1A1ACHEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3247734-B1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-08-31 EP disclosed
US-10370491-B2 Preparation of highly heat-resistant (co)polycarbonates by the transesterification method COVESTRO DEUTSCHLAND AG (DE) 2019-08-06 US disclosed
US-20170369642-A1 Preparation of Highly Heat-Resistant (Co)Polycarbonates by the Transesterification Method COVESTRO DEUTSCHLAND AG (DE) 2017-12-28 US disclosed
EP-3247734-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD Covestro Deutschland AG (DE) 2017-11-29 EP disclosed
WO-2016116480-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO DEUTSCHLAND AG (DE) 2016-07-28 WO disclosed
US-20090117314-A1 PROCESS FOR THE PREPARATION OF POLYCARBONATE BY THE MELT TRANSESTERIFICATION METHOD BAYER MATERIALSCIENCE AG (DE) 2009-05-07 US disclosed