SCHEMBL4342986

SCHEMBL4342986

CC(C)Oc1ccccc1COC(=O)Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 4/20 0.46
HTR2A P28223 1/20 0.45
ALDH1A1 P00352 3/20 0.43
ACHE P22303 1/20 0.43
TSPO P30536 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
LMNA P02545 2/20 0.43
MEN1 O00255 1/20 0.43
TP53 P04637 1/20 0.43
GAA P10253 1/20 0.43
KMT2A Q03164 1/20 0.43
IRAK4 Q9NWZ3 2/20 0.42
POLB P06746 1/20 0.41
KDM4E B2RXH2 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
ELANE P08246 1/20 0.40
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
SLC16A3 O15427 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4332055 0.88 FFAR4 (0.49) FFAR4ALDH1A1ACHETSPOLMNA
SCHEMBL4335280 0.83 FOS (0.45) ALDH1A1LMNAKDM4EELANEMTNR1A
SCHEMBL6150724 0.82 FFAR1 (0.51) FFAR4ALDH1A1LMNAMEN1GAA
SCHEMBL25720977 0.82 FFAR4 (0.49) FFAR4ALDH1A1ACHETSPONPC1
SCHEMBL4343859 0.81 L3MBTL1 (0.47) ALDH1A1LMNAMEN1TP53GAA
SCHEMBL4334989 0.80 L3MBTL1 (0.40) FFAR4HTR2AMEN1TP53KMT2A
SCHEMBL11393662 0.79 IRAK4 (0.54) FFAR4ALDH1A1ACHETSPOLMNA
SCHEMBL4342476 0.79 BCHE (0.42) ALDH1A1ACHENPC1RAB9ALMNA
SCHEMBL6151614 0.78 HTR1A (0.51) ALDH1A1LMNAMEN1TP53GAA
SCHEMBL4332062 0.78 PPARD (0.46) ALDH1A1LMNAMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3247734-B1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-08-31 EP disclosed
US-10370491-B2 Preparation of highly heat-resistant (co)polycarbonates by the transesterification method COVESTRO DEUTSCHLAND AG (DE) 2019-08-06 US disclosed
US-20170369642-A1 Preparation of Highly Heat-Resistant (Co)Polycarbonates by the Transesterification Method COVESTRO DEUTSCHLAND AG (DE) 2017-12-28 US disclosed
EP-3247734-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD Covestro Deutschland AG (DE) 2017-11-29 EP disclosed
WO-2016116480-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO DEUTSCHLAND AG (DE) 2016-07-28 WO disclosed
US-20090117314-A1 PROCESS FOR THE PREPARATION OF POLYCARBONATE BY THE MELT TRANSESTERIFICATION METHOD BAYER MATERIALSCIENCE AG (DE) 2009-05-07 US disclosed