SCHEMBL4332087

SCHEMBL4332087

C=C(C)C(N)=O.CC(C)(CO)CO

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.60
LMNA P02545 1/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL414549 0.87 TDP1 (0.63) TDP1LMNAALOX15BLMPMP22
Methacrylic Acid SCHEMBL15667140 0.82 TET2 (0.38) TDP1KDM4E
Methacrylic Acid SCHEMBL505626 0.82 TET2 (0.38) TDP1KDM4E
Methacrylic Acid SCHEMBL18812640 0.82 TET2 (0.38) TDP1KDM4E
Methacrylic Acid SCHEMBL23107 0.82 TET2 (0.38) TDP1KDM4E
Methacrylic Acid SCHEMBL23611338 0.82 TET2 (0.38) TDP1KDM4E
SCHEMBL4342621 0.82 TDP1 (0.63) TDP1LMNAALOX15BLMPMP22
Methacrylic Acid SCHEMBL8509424 0.82 TET2 (0.38) TDP1KDM4E
Methacrylic Acid SCHEMBL4382808 0.82 TET2 (0.38) TDP1KDM4E
Tromethamine SCHEMBL2097922 0.80 TDP1 (0.60) TDP1LMNAALOX15BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090264551-A1 Photocurable fixture for orthopedic surgery background of the invention ALCARE CO., LTD. 2009-10-22 US disclosed