Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4326973 | 0.88 | CHRM3 (0.45) | CHRM3BCHE | |
| SCHEMBL13914074 | 0.85 | CCR3 (0.53) | CHRM3BCHE | |
| SCHEMBL4331210 | 0.85 | BCHE (0.53) | CHRM3BCHE | |
| SCHEMBL13914070 | 0.84 | BCHE (0.55) | CHRM3BCHE | |
| SCHEMBL13913969 | 0.77 | GRM2 (0.46) | — | |
| SCHEMBL27692169 | 0.77 | L3MBTL1 (0.44) | — | |
| SCHEMBL4319479 | 0.77 | MAPT (0.44) | — | |
| SCHEMBL4341390 | 0.76 | CHRM5 (0.41) | CHRM3BCHE | |
| SCHEMBL4331363 | 0.76 | POLB (0.41) | BCHE | |
| SCHEMBL5317082 | 0.74 | ALDH1A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069340-A1 | Pyrazolone Compounds As Metabotropic Glutamate Receptor Agonists For The Treatment Of Neurological And Psychiatric Disorders | ASTRAZENECA AB (SE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069340-A1 | Pyrazolone Compounds As Metabotropic Glutamate Receptor Agonists For The Treatment Of Neurological And Psychiatric Disorders | GRIN1, GRM1, GRIN3A | CHRM3 110/4885BCHE 1608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.