SCHEMBL4332808

SCHEMBL4332808

CC(C)(C)Oc1ccccc1C(=O)OC(=O)OC(=O)c1ccccc1OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.42
MAPT P10636 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HSD17B10 Q99714 5/20 0.40
KDM4E B2RXH2 4/20 0.40
SLC6A3 Q01959 3/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 4/20 0.39
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 4/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
ESR1 P03372 1/20 0.37
ITGB3 P05106 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4334988 0.88 MAPT (0.46) ELANEMAPTNPSR1HSD17B10KDM4E
SCHEMBL6467074 0.85 ELANE (0.44) ELANEMAPTNPSR1HSD17B10KDM4E
SCHEMBL3452774 0.85 ELANE (0.44) ELANEMAPTNPSR1HSD17B10KDM4E
SCHEMBL448369 0.84 ELANE (0.43) ELANEMAPTNPSR1HSD17B10KDM4E
SCHEMBL8127239 0.82 ELANE (0.42) ELANEMAPTNPSR1HSD17B10KDM4E
SCHEMBL5884931 0.82 ELANE (0.42) ELANEMAPTNPSR1HSD17B10KDM4E
SCHEMBL17637541 0.82 ELANE (0.42) ELANEMAPTNPSR1HSD17B10KDM4E
SCHEMBL28002516 0.82 ELANE (0.42) ELANEMAPTNPSR1HSD17B10KDM4E
SCHEMBL1023381 0.82 ELANE (0.42) ELANEMAPTNPSR1HSD17B10KDM4E
SCHEMBL450603 0.82 ELANE (0.42) ELANEMAPTNPSR1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3247734-B1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-08-31 EP disclosed
US-10370491-B2 Preparation of highly heat-resistant (co)polycarbonates by the transesterification method COVESTRO DEUTSCHLAND AG (DE) 2019-08-06 US disclosed
US-20170369642-A1 Preparation of Highly Heat-Resistant (Co)Polycarbonates by the Transesterification Method COVESTRO DEUTSCHLAND AG (DE) 2017-12-28 US disclosed
EP-3247734-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD Covestro Deutschland AG (DE) 2017-11-29 EP disclosed
WO-2016116480-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO DEUTSCHLAND AG (DE) 2016-07-28 WO disclosed
US-20090117314-A1 PROCESS FOR THE PREPARATION OF POLYCARBONATE BY THE MELT TRANSESTERIFICATION METHOD BAYER MATERIALSCIENCE AG (DE) 2009-05-07 US disclosed