Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467856 | 0.88 | MAPT (0.57) | MAPTNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4332808 | 0.88 | ELANE (0.42) | MAPTNPSR1CYP1A2CYP2C9HSD17B10 | |
| Bicarbonate SCHEMBL29984060 | 0.86 | MAPT (0.56) | MAPTNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2228969 | 0.83 | HPGD (0.56) | MAPTNPSR1CYP1A2CYP2C9CYP2C19 | |
| Bicarbonate SCHEMBL6654633 | 0.82 | HPGD (0.55) | MAPTNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5689370 | 0.81 | CTNNB1 (0.57) | MAPTNPSR1HSD17B10ALDH1A1TSHR | |
| SCHEMBL4342985 | 0.79 | IRAK4 (0.54) | MAPTNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4343858 | 0.79 | ESR1 (0.51) | MAPTNPSR1ALDH1A1KMT2ALMNA | |
| SCHEMBL238619 | 0.79 | KDM4E (0.56) | MAPTNPSR1CYP1A2CYP2C9CYP2C19 | |
| Bicarbonate SCHEMBL7114860 | 0.78 | ESR1 (0.50) | MAPTNPSR1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247734-B1 | PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2022-08-31 | — | — | EP | disclosed |
| US-10370491-B2 | Preparation of highly heat-resistant (co)polycarbonates by the transesterification method | COVESTRO DEUTSCHLAND AG (DE) | 2019-08-06 | — | — | US | disclosed |
| US-20170369642-A1 | Preparation of Highly Heat-Resistant (Co)Polycarbonates by the Transesterification Method | COVESTRO DEUTSCHLAND AG (DE) | 2017-12-28 | — | — | US | disclosed |
| EP-3247734-A1 | PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD | Covestro Deutschland AG (DE) | 2017-11-29 | — | — | EP | disclosed |
| WO-2016116480-A1 | PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD | COVESTRO DEUTSCHLAND AG (DE) | 2016-07-28 | — | — | WO | disclosed |
| US-20090117314-A1 | PROCESS FOR THE PREPARATION OF POLYCARBONATE BY THE MELT TRANSESTERIFICATION METHOD | BAYER MATERIALSCIENCE AG (DE) | 2009-05-07 | — | — | US | disclosed |