SCHEMBL6467074

SCHEMBL6467074

CC(C)(C)Oc1ccccc1C(=O)OOC(=O)c1ccccc1OC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.44
MAPT P10636 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HSD17B10 Q99714 4/20 0.43
ALDH1A1 P00352 4/20 0.43
TSHR P16473 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
KDM4E B2RXH2 3/20 0.42
SLC6A3 Q01959 3/20 0.42
LMNA P02545 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
HPGD P15428 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ESR1 P03372 2/20 0.39
ITGB3 P05106 1/20 0.39
ITGA2B P08514 1/20 0.39
HMGB1 P09429 1/20 0.39
GGT1 P19440 1/20 0.39
PTGS1 P23219 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3452774 0.89 ELANE (0.44) ELANEMAPTNPSR1HSD17B10ALDH1A1
SCHEMBL448369 0.87 ELANE (0.43) ELANEMAPTNPSR1HSD17B10ALDH1A1
SCHEMBL4332808 0.85 ELANE (0.42) ELANEMAPTNPSR1HSD17B10ALDH1A1
SCHEMBL17637541 0.85 ELANE (0.42) ELANEMAPTNPSR1HSD17B10ALDH1A1
SCHEMBL5884931 0.85 ELANE (0.42) ELANEMAPTNPSR1HSD17B10ALDH1A1
SCHEMBL1023381 0.85 ELANE (0.42) ELANEMAPTNPSR1HSD17B10ALDH1A1
SCHEMBL450603 0.85 ELANE (0.42) ELANEMAPTNPSR1HSD17B10ALDH1A1
SCHEMBL8127239 0.85 ELANE (0.42) ELANEMAPTNPSR1HSD17B10ALDH1A1
SCHEMBL28002516 0.85 ELANE (0.42) ELANEMAPTNPSR1HSD17B10ALDH1A1
SCHEMBL30526883 0.82 LMNA (0.53) ELANEMAPTHSD17B10ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6951904-B1 Process for increasing the melt strength of polypropylene POLYMERS AUSTRALIA PTY LIMITED (AU) 2005-10-04 US claimed
EP-1080148-A4 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LTD (AU) 2003-02-05 EP claimed
EP-1080148-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE Polymers Australia PTY Limited (AU) 2001-03-07 EP claimed
WO-1999036466-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LIMITED (AU) 1999-07-22 WO claimed
US-6951904-B1 Process for increasing the melt strength of polypropylene POLYMERS AUSTRALIA PTY LIMITED (AU) 2005-10-04 US disclosed
EP-1080148-A4 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LTD (AU) 2003-02-05 EP disclosed
EP-1080148-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE Polymers Australia PTY Limited (AU) 2001-03-07 EP disclosed
WO-1999036466-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LIMITED (AU) 1999-07-22 WO disclosed