⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408343 | 0.87 | — | — | |
| SCHEMBL667439 | 0.83 | — | — | |
| SCHEMBL21617961 | 0.77 | — | — | |
| SCHEMBL756507 | 0.77 | TRIM24 (0.43) | — | |
| SCHEMBL3424537 | 0.77 | — | — | |
| SCHEMBL3431164 | 0.72 | — | — | |
| SCHEMBL56072 | 0.67 | MAOA (0.54) | — | |
| SCHEMBL3431239 | 0.65 | — | — | |
| SCHEMBL2373729 | 0.65 | — | — | |
| SCHEMBL383299 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4295852-A2 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | Syros Pharmaceuticals, Inc. (US) | 2023-12-27 | — | — | EP | claimed |
| EP-3484871-B1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | claimed |
| US-20230062491-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | MEDIC LIFE SCIENCES, INC. | 2023-03-02 | — | — | US | claimed |
| US-20230000870-A1 | METHODS OF TREATING CANCER IN BIOMARKER-IDENTIFIED PATIENTS WITH INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2023-01-05 | — | — | US | claimed |
| CN-114901284-A | Methods of treating cancer in patients identified by biomarkers with cyclin dependent kinase 7(CDK7) inhibitors | 希洛斯医药品股份有限公司 | 2022-08-12 | — | — | CN | claimed |
| WO-2021087138-A1 | METHODS OF TREATING CANCER IN BIOMARKER-IDENTIFIED PATIENTS WITH INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2021-05-06 | — | — | WO | claimed |
| EP-3484871-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | Syros Pharmaceuticals, Inc. (US) | 2019-05-22 | — | — | EP | claimed |
| CN-109096415-A | The preparation method of catalyst component for olefin polymerization and preparation method thereof and olefin polymerization catalysis and olefin polymer | 中国石油化工股份有限公司 | 2018-12-28 | — | — | CN | claimed |
| CN-109096416-A | The preparation method of catalyst component for olefin polymerization and preparation method thereof and olefin polymerization catalysis and olefin polymer | 中国石油化工股份有限公司 | 2018-12-28 | — | — | CN | claimed |
| WO-2018013867-A1 | INHIBITORS OF CYCLIN DEPENDNT KINASE 7 (CDK7) | MARINEAU JASON J (US) | 2018-01-18 | — | — | WO | claimed |
| CN-106242071-A | Hexavalent chromium polluted composite resin adsorbent and preparation method thereof in a kind of steel and iron industry sewage | 王维娜 | 2016-12-21 | — | — | CN | claimed |
| EP-4295852-A2 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | Syros Pharmaceuticals, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3484871-B1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20230062491-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | MEDIC LIFE SCIENCES, INC. | 2023-03-02 | — | — | US | disclosed |
| US-20230000870-A1 | METHODS OF TREATING CANCER IN BIOMARKER-IDENTIFIED PATIENTS WITH INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2023-01-05 | — | — | US | disclosed |
| WO-1998057937-A2 | INHIBITORS OF FACTOR XA WITH A NEUTRAL P1 SPECIFICITY GROUP | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-23 | — | — | WO | disclosed |
| US-5468732-A | Hypotensive | PFIZER INC. (US) | 1995-11-21 | — | — | US | disclosed |
| EP-0385593-A1 | Phosphorus containing renin inhibitors | PFIZER INC. (US) | 1990-09-05 | — | — | EP | disclosed |
| WO-1990009172-A1 | PHOSPHORUS CONTAINING RENIN INHIBITORS | PFIZER INC. (US) | 1990-08-23 | — | — | WO | disclosed |
| US-4003911-A | ANTISECRETORY AGENTS, OXYTOCICS, BRONCHODILATORS, PLASTICIZERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-01-18 | — | — | US | disclosed |